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Genes and Chromosomes of Leishmania infantum

Overview of attention for article published in Memórias do Instituto Oswaldo Cruz, October 1998
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Title
Genes and Chromosomes of Leishmania infantum
Published in
Memórias do Instituto Oswaldo Cruz, October 1998
DOI 10.1590/s0074-02761997000600022
Pubmed ID
Authors

Jose María Requena, Manuel Soto, Luis Quijada, Carlos Alonso

Abstract

During recent years, several Leishmania infantum genes have been cloned and characterized. Here, we have summarized the available information on the gene organization and expression in this protozoan parasite. From a comparative analysis, the following outstanding features were found to be common to most of the genes characterized: tandemly organized genes with conserved coding regions and divergent untranslated regions, polycistronic transcription and post-transcriptional regulation of gene expression. The analysis of chromosomes of L. infantum by pulsed-field electrophoresis showed the existence of both size and number polymorphisms such that each strain has a distinctive molecular karyotype. Despite this variability, highly conserved physical linkage groups exists among different strains of L. infantum and even among Old World Leishmania species. Gene mapping on the L. infantum molecular karyotype evidenced a bias in chromosomal distribution of, at least, the evolutionary conserved genes.

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Mendeley readers

The data shown below were compiled from readership statistics for 30 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
France 1 3%
Unknown 29 97%

Demographic breakdown

Readers by professional status Count As %
Researcher 7 23%
Professor > Associate Professor 4 13%
Student > Master 4 13%
Student > Bachelor 2 7%
Professor 2 7%
Other 7 23%
Unknown 4 13%
Readers by discipline Count As %
Agricultural and Biological Sciences 10 33%
Biochemistry, Genetics and Molecular Biology 8 27%
Medicine and Dentistry 3 10%
Chemistry 2 7%
Environmental Science 1 3%
Other 1 3%
Unknown 5 17%
Attention Score in Context

Attention Score in Context

This research output has an Altmetric Attention Score of 1. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 01 November 2012.
All research outputs
#22,759,452
of 25,373,627 outputs
Outputs from Memórias do Instituto Oswaldo Cruz
#1,299
of 1,502 outputs
Outputs of similar age
#31,281
of 32,030 outputs
Outputs of similar age from Memórias do Instituto Oswaldo Cruz
#28
of 31 outputs
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