Title |
First detection of a human astrovirus type 8 in a child with diarrhea in Belém, Brazil: comparison with other strains worldwide and identification of possible three lineages
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Published in |
Memórias do Instituto Oswaldo Cruz, April 2007
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DOI | 10.1590/s0074-02762007005000032 |
Pubmed ID | |
Authors |
Yvone B Gabbay, Alexandre C Linhares, Darleise S Oliveira, Lilian S Nakamura, Joana D'Arc P Mascarenhas, Rosa Helena P Gusmão, Marcos B Heinemann, Olinda Macêdo, José Paulo G Leite |
Abstract |
This study describes the genetic relationships of the first human astrovirus type-8 (HAstV-8) detected in Belém-Brazil, during a public hospital-based study. This strain was compared with other HAstV-8 strains identified elsewhere which have sequences available at GeneBank. The regions ORF1a (primers Mon348/Mon340) and ORF2 (primers Mon269/Mon270) were analyzed by nucleotide sequencing and a high similarity rate was observed among the Belém strain and other HAstV-8 strains. In ORF1a, homology values of 93-100% were detected, and in ORF2 96-99%. Considering the sequence variation (7%) observed in ORF2 region, it was suggested that HAstV-8 strains could be divided in three different lineages. |
X Demographics
Geographical breakdown
Country | Count | As % |
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Unknown | 1 | 100% |
Demographic breakdown
Type | Count | As % |
---|---|---|
Members of the public | 1 | 100% |
Mendeley readers
Geographical breakdown
Country | Count | As % |
---|---|---|
Brazil | 1 | 5% |
Unknown | 19 | 95% |
Demographic breakdown
Readers by professional status | Count | As % |
---|---|---|
Student > Bachelor | 5 | 25% |
Student > Master | 4 | 20% |
Researcher | 3 | 15% |
Professor > Associate Professor | 2 | 10% |
Student > Ph. D. Student | 1 | 5% |
Other | 3 | 15% |
Unknown | 2 | 10% |
Readers by discipline | Count | As % |
---|---|---|
Agricultural and Biological Sciences | 7 | 35% |
Biochemistry, Genetics and Molecular Biology | 5 | 25% |
Medicine and Dentistry | 3 | 15% |
Nursing and Health Professions | 1 | 5% |
Immunology and Microbiology | 1 | 5% |
Other | 1 | 5% |
Unknown | 2 | 10% |