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Genotyping of multidrug-resistant strains of Pseudomonas aeruginosa isolated from burn and wound infections by ERIC-PCR1

Overview of attention for article published in Acta Cirúrgica Brasileira, March 2016
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Title
Genotyping of multidrug-resistant strains of Pseudomonas aeruginosa isolated from burn and wound infections by ERIC-PCR1
Published in
Acta Cirúrgica Brasileira, March 2016
DOI 10.1590/s0102-865020160030000009
Pubmed ID
Authors

Azar Dokht Khosravi, Hajar Hoveizavi, Ali Mohammadian, Abbas Farahani, Atefeh Jenabi

Abstract

To determine the genetic diversity of MDR P. aeruginosa strains isolated from burn and wound infections in Ahvaz, Iran, by ERIC-PCR. From total 99 strains of P. aeruginosa defined as MDR by using drug susceptibility testing, 66 were subjected to ERIC-PCR analysis, comprises 53 strains isolated from burn infection, and 13 randomly selected strains from wound infection with higher resistance to combinations of more numbers of drugs. Eight clusters (I to VIII), and 50 single clones were generated for tested MDR isolates analyzed by ERIC-PCR. The high heterogeneity was observed among the isolates from burn infections including 16 isolates which were categorized in eight clusters and 37 single clones. The isolates in clusters II, III, VI, VIII showed 100% similarity. The high level of genotypic heterogeneity in P. aeruginosa strains demonstrated no genetic correlation between them. Extremely high drug resistance in isolates from burn, suggests that efficient control measures and proper antibiotic policy should be observed.

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Mendeley readers

The data shown below were compiled from readership statistics for 51 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
Hungary 1 2%
Unknown 50 98%

Demographic breakdown

Readers by professional status Count As %
Student > Doctoral Student 7 14%
Student > Ph. D. Student 6 12%
Researcher 6 12%
Lecturer 6 12%
Student > Bachelor 3 6%
Other 11 22%
Unknown 12 24%
Readers by discipline Count As %
Immunology and Microbiology 15 29%
Medicine and Dentistry 7 14%
Agricultural and Biological Sciences 5 10%
Pharmacology, Toxicology and Pharmaceutical Science 3 6%
Environmental Science 2 4%
Other 4 8%
Unknown 15 29%