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Antioxidant effects of açaí seed ( Euterpe oleracea ) in anorexia-cachexia syndrome induced by Walker-256 tumor1

Overview of attention for article published in Acta Cirúrgica Brasileira, September 2016
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Title
Antioxidant effects of açaí seed ( Euterpe oleracea ) in anorexia-cachexia syndrome induced by Walker-256 tumor1
Published in
Acta Cirúrgica Brasileira, September 2016
DOI 10.1590/s0102-865020160090000004
Pubmed ID
Authors

Vitor Hugo Nunes do Nascimento, Carla dos Santos Lima, Jorge Tadeu Campos Paixão, Jofre Jacob da Silva Freitas, Katia Simone Kietzer

Abstract

To assess antioxidant effects of açaí seed extract on anorexia-cachexia induced by Walker-256 tumor. A population of 20 lab rats were distributed into four groups (n=5): Control Group (CG), which only received tumor inoculation. Experimental Group-100 (EG-100), with animals submitted to tumor inoculation and treated with seed extract in a 100 mg / ml concentration through gavage. Experimental Group-200 (EG-200), with animals submitted to tumor inoculation and treated with seed extract in a 200 mg / ml concentration. Placebo Group (GP), which received tumor inoculation and ethanol-water solution. We analyzed proteolysis, lipid peroxidation, tumor diameter and weight. Lipid peroxidation was representative only in the cerebral cortex, where there was more oxidative stress in rats treated with the extract (p = 0.0276). For proteolysis, there was less muscle damage in untreated rats (p = 0.0312). Only tumor diameter in treated rats was significantly lower (p = 0.0200) compared to untreated ones. The açaí seed extract showed no beneficial effect on the general framework of the cachectic syndrome in lab rats. However, some anticarcinogenic effects were observed in the tumor diameter and weight.

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The data shown below were compiled from readership statistics for 41 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
Unknown 41 100%

Demographic breakdown

Readers by professional status Count As %
Student > Bachelor 10 24%
Student > Master 9 22%
Student > Doctoral Student 3 7%
Librarian 2 5%
Student > Postgraduate 2 5%
Other 4 10%
Unknown 11 27%
Readers by discipline Count As %
Medicine and Dentistry 6 15%
Biochemistry, Genetics and Molecular Biology 5 12%
Engineering 4 10%
Pharmacology, Toxicology and Pharmaceutical Science 3 7%
Psychology 3 7%
Other 7 17%
Unknown 13 32%