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C-reactive protein and its relation to high blood pressure in overweight or obese children and adolescents

Overview of attention for article published in Revista Paulista de Pediatria, September 2013
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Title
C-reactive protein and its relation to high blood pressure in overweight or obese children and adolescents
Published in
Revista Paulista de Pediatria, September 2013
DOI 10.1590/s0103-05822013000300009
Pubmed ID
Authors

Juliana Andreia F. Noronha, Carla Campos M. Medeiros, Anajás da Silva Cardoso, Nathalia Costa Gonzaga, Alessandra Teixeira Ramos, André Luiz C. Ramos

Abstract

OBJECTIVE To investigate the association between C-reactive protein (CRP) and high blood pressure (BP) in overweight or obese children and adolescents. METHODS Cross-sectional study with 184 overweight or obese children and adolescents aged from two to 18 years old, from April, 2009 to April, 2010. The classification of nutritional status used the body mass index (BMI). Based on the Centers for Disease Control and Prevention curve, individuals were classified as: overweight (BMI between the 85th-95th percentiles), obesity (BMI between 95th-97th percentiles) and severe obesity (BMI >97th percentile). Abnormal values were considered for systolic BP (SBP) and/or diastolic (DBP) if ≥ 90th percentile of the BP curve recommended for children and adolescents in the V Brazilian Guidelines on Hypertension, for waist circumference (WC) if ≥ 90th percentile of the curve established by the National Cholesterol Education Program, and for high sensitive CRP (hs-CRP) if >3mg/dL. To evaluate the association of inadequate values of CRP and the studied groups, chi-square test and analysis of variance were applied, using the Statistical Package for the Social Sciences version 17.0 and adopting a significance level of 5%. RESULTS Among the evaluated sample, 66.3% were female, 63.5%, non-white, 64.1% had severe obesity, 78.3% had altered WC and 70.6% presented high BP. There was a significant association of CRP high levels with altered WC and BMI ≥ 97 th percentile. In adolescents, high CRP was related to high SBP. CRP mean values were higher in individuals with elevated SBP. CONCLUSIONS Inadequate values of hs-CRP were associated with severe obesity and high SBP in the studied population. These markers can be used to identify children and adolescents at higher risk for developing atherosclerosis.

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Mendeley readers

Mendeley readers

The data shown below were compiled from readership statistics for 33 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
Unknown 33 100%

Demographic breakdown

Readers by professional status Count As %
Student > Doctoral Student 2 6%
Student > Bachelor 1 3%
Professor 1 3%
Student > Master 1 3%
Student > Postgraduate 1 3%
Other 0 0%
Unknown 27 82%
Readers by discipline Count As %
Medicine and Dentistry 4 12%
Sports and Recreations 1 3%
Nursing and Health Professions 1 3%
Unknown 27 82%
Attention Score in Context

Attention Score in Context

This research output has an Altmetric Attention Score of 1. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 22 October 2013.
All research outputs
#19,945,185
of 25,374,917 outputs
Outputs from Revista Paulista de Pediatria
#249
of 511 outputs
Outputs of similar age
#154,578
of 212,480 outputs
Outputs of similar age from Revista Paulista de Pediatria
#5
of 9 outputs
Altmetric has tracked 25,374,917 research outputs across all sources so far. This one is in the 18th percentile – i.e., 18% of other outputs scored the same or lower than it.
So far Altmetric has tracked 511 research outputs from this source. They receive a mean Attention Score of 4.1. This one is in the 46th percentile – i.e., 46% of its peers scored the same or lower than it.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 212,480 tracked outputs that were published within six weeks on either side of this one in any source. This one is in the 24th percentile – i.e., 24% of its contemporaries scored the same or lower than it.
We're also able to compare this research output to 9 others from the same source and published within six weeks on either side of this one. This one has scored higher than 4 of them.