Title |
Angioedema adquirido autoimune de difícil controle em paciente com lúpus eritematoso sistêmico
|
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Published in |
Advances in Rheumatology, February 2010
|
DOI | 10.1590/s0482-50042010000100011 |
Pubmed ID | |
Authors |
Vilson Furlanetto, Karina de Souza Giassi, Fabrício de Souza Neves, Adriana Fontes Zimmermann, Gláucio Ricardo Werner Castro, Ivânio Alves Pereira |
Abstract |
Acquired angioedema is caused by different drugs and lymphoproliferative diseases, and rarely it has also been related to the presence of auto-immune disorders. We report the case of a 47 year old female with systemic lupus erythematosus (SLE) and severe cutaneous involvement who developed recurrent localized angioedema of the face, including lips and eye lids, upper limbs, and thorax, not associated with urticaria, and with reduced levels of C1 esterase inhibitor. Treatment with antimalarials, glucocorticoids, and pulse therapy with methylprednisolone associated with azathioprine did not improve her condition. The patient was also unsuccessfully treated with danazol, and she only showed clinical response after several sessions of plasmapheresis, including resolution of the extensive edema of the gastrointestinal tract. |
Mendeley readers
Geographical breakdown
Country | Count | As % |
---|---|---|
United Kingdom | 1 | 7% |
Unknown | 13 | 93% |
Demographic breakdown
Readers by professional status | Count | As % |
---|---|---|
Researcher | 4 | 29% |
Other | 3 | 21% |
Professor | 3 | 21% |
Student > Doctoral Student | 1 | 7% |
Student > Bachelor | 1 | 7% |
Other | 2 | 14% |
Readers by discipline | Count | As % |
---|---|---|
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Psychology | 2 | 14% |
Agricultural and Biological Sciences | 1 | 7% |
Biochemistry, Genetics and Molecular Biology | 1 | 7% |
Chemistry | 1 | 7% |
Other | 0 | 0% |
Unknown | 2 | 14% |