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Dermatomiosite juvenil: revisão e atualização em patogênese e tratamento

Overview of attention for article published in Advances in Rheumatology, June 2010
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Title
Dermatomiosite juvenil: revisão e atualização em patogênese e tratamento
Published in
Advances in Rheumatology, June 2010
DOI 10.1590/s0482-50042010000300010
Pubmed ID
Authors

Nilton Salles Rosa Neto, Cláudia Goldenstein-Schainberg

Abstract

Juvenile dermatomyositis (JDM) is an autoimmune disease characterized by systemic vasculopathy. Its main manifestations include symmetrical proximal muscle weakness, elevated serum muscle enzymes and cutaneous lesions, among which the heliotrope and Gottron's papules are pathognomonic. Early recognition and prompt therapy allow better prognosis and prevent the development of calcinosis. Although the treatment is based on glucocorticoids, the more commonly associated immunosuppressors include methotrexate, azathioprine, cyclosporine, and cyclophosphamide, depending on the severity of disease. The use of immunobiologicals for refractory cases remains under investigation, but the results are controversial or inexpressive. In this review, we highlight recent updates on the pathogenesis and treatment of JDM.

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Mendeley readers

The data shown below were compiled from readership statistics for 14 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
Unknown 14 100%

Demographic breakdown

Readers by professional status Count As %
Student > Bachelor 9 64%
Student > Master 3 21%
Student > Postgraduate 1 7%
Unknown 1 7%
Readers by discipline Count As %
Medicine and Dentistry 8 57%
Nursing and Health Professions 3 21%
Agricultural and Biological Sciences 1 7%
Arts and Humanities 1 7%
Unknown 1 7%