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X Demographics
Mendeley readers
Attention Score in Context
| Title |
Population analysis of vitamin D receptor polymorphisms and the role of genetic ancestry in an admixed population
|
|---|---|
| Published in |
Genetics and Molecular Biology, July 2011
|
| DOI | 10.1590/s1415-47572011000300003 |
| Pubmed ID | |
| Authors |
Tulio C. Lins, Rodrigo G. Vieira, Dario Grattapaglia, Rinaldo W. Pereira |
| Abstract |
The vitamin D receptor (VDR) is an essential protein related to bone metabolism. Some VDR alleles are differentially distributed among ethnic populations and display variable patterns of linkage disequilibrium (LD). In this study, 200 unrelated Brazilians were genotyped using 21 VDR single nucleotide polymorphisms (SNPs) and 28 ancestry informative markers. The patterns of LD and haplotype distribution were compared among Brazilian and the HapMap populations of African (YRI), European (CEU) and Asian (JPT+CHB) origins. Conditional regression and haplotype-specific analysis were performed using estimates of individual genetic ancestry in Brazilians as a quantitative trait. Similar patterns of LD were observed in the 5' and 3' gene regions. However, the frequency distribution of haplotype blocks varied among populations. Conditional regression analysis identified haplotypes associated with European and Amerindian ancestry, but not with the proportion of African ancestry. Individual ancestry estimates were associated with VDR haplotypes. These findings reinforce the need to correct for population stratification when performing genetic association studies in admixed populations. |
X Demographics
The data shown below were collected from the profiles of 2 X users who shared this research output. Click here to find out more about how the information was compiled.
Geographical breakdown
| Country | Count | As % |
|---|---|---|
| United States | 1 | 50% |
| Unknown | 1 | 50% |
Demographic breakdown
| Type | Count | As % |
|---|---|---|
| Members of the public | 2 | 100% |
Mendeley readers
The data shown below were compiled from readership statistics for 60 Mendeley readers of this research output. Click here to see the associated Mendeley record.
Geographical breakdown
| Country | Count | As % |
|---|---|---|
| United States | 1 | 2% |
| Uruguay | 1 | 2% |
| France | 1 | 2% |
| Brazil | 1 | 2% |
| Unknown | 56 | 93% |
Demographic breakdown
| Readers by professional status | Count | As % |
|---|---|---|
| Student > Master | 11 | 18% |
| Student > Bachelor | 8 | 13% |
| Professor | 6 | 10% |
| Professor > Associate Professor | 6 | 10% |
| Researcher | 5 | 8% |
| Other | 12 | 20% |
| Unknown | 12 | 20% |
| Readers by discipline | Count | As % |
|---|---|---|
| Agricultural and Biological Sciences | 21 | 35% |
| Biochemistry, Genetics and Molecular Biology | 8 | 13% |
| Medicine and Dentistry | 6 | 10% |
| Nursing and Health Professions | 4 | 7% |
| Immunology and Microbiology | 2 | 3% |
| Other | 3 | 5% |
| Unknown | 16 | 27% |
Attention Score in Context
This research output has an Altmetric Attention Score of 1. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 15 August 2011.
All research outputs
#17,286,379
of 25,374,917 outputs
Outputs from Genetics and Molecular Biology
#408
of 771 outputs
Outputs of similar age
#93,078
of 127,145 outputs
Outputs of similar age from Genetics and Molecular Biology
#7
of 8 outputs
Altmetric has tracked 25,374,917 research outputs across all sources so far. This one is in the 21st percentile – i.e., 21% of other outputs scored the same or lower than it.
So far Altmetric has tracked 771 research outputs from this source. They receive a mean Attention Score of 4.8. This one is in the 32nd percentile – i.e., 32% of its peers scored the same or lower than it.
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We're also able to compare this research output to 8 others from the same source and published within six weeks on either side of this one.