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MHC Class II haplotypes of Colombian Amerindian tribes

Overview of attention for article published in Genetics and Molecular Biology, April 2013
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Title
MHC Class II haplotypes of Colombian Amerindian tribes
Published in
Genetics and Molecular Biology, April 2013
DOI 10.1590/s1415-47572013005000014
Pubmed ID
Authors

Juan J. Yunis, Edmond J. Yunis, Emilio Yunis

Abstract

We analyzed 1041 individuals belonging to 17 Amerindian tribes of Colombia, Chimila, Bari and Tunebo (Chibcha linguistic family), Embera, Waunana (Choco linguistic family), Puinave and Nukak (Maku-Puinave linguistic families), Cubeo, Guanano, Tucano, Desano and Piratapuyo (Tukano linguistic family), Guahibo and Guayabero (Guayabero Linguistic Family), Curripaco and Piapoco (Arawak linguistic family) and Yucpa (Karib linguistic family). for MHC class II haplotypes (HLA-DRB1, DQA1, DQB1). Approximately 90% of the MHC class II haplotypes found among these tribes are haplotypes frequently encountered in other Amerindian tribes. Nonetheless, striking differences were observed among Chibcha and non-Chibcha speaking tribes. The DRB1*04:04, DRB1*04:11, DRB1*09:01 carrying haplotypes were frequently found among non-Chibcha speaking tribes, while the DRB1*04:07 haplotype showed significant frequencies among Chibcha speaking tribes, and only marginal frequencies among non-Chibcha speaking tribes. Our results suggest that the differences in MHC class II haplotype frequency found among Chibcha and non-Chibcha speaking tribes could be due to genetic differentiation in Mesoamerica of the ancestral Amerindian population into Chibcha and non-Chibcha speaking populations before they entered into South America.

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Mendeley readers

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Geographical breakdown

Country Count As %
Unknown 18 100%

Demographic breakdown

Readers by professional status Count As %
Researcher 4 22%
Student > Ph. D. Student 3 17%
Student > Bachelor 2 11%
Professor 2 11%
Student > Master 2 11%
Other 2 11%
Unknown 3 17%
Readers by discipline Count As %
Biochemistry, Genetics and Molecular Biology 5 28%
Agricultural and Biological Sciences 4 22%
Social Sciences 3 17%
Immunology and Microbiology 1 6%
Medicine and Dentistry 1 6%
Other 1 6%
Unknown 3 17%
Attention Score in Context

Attention Score in Context

This research output has an Altmetric Attention Score of 1. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 17 June 2013.
All research outputs
#20,656,161
of 25,374,647 outputs
Outputs from Genetics and Molecular Biology
#551
of 771 outputs
Outputs of similar age
#162,932
of 212,311 outputs
Outputs of similar age from Genetics and Molecular Biology
#13
of 17 outputs
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