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Vanishing bile duct syndrome in Hodgkin's disease: case report

Overview of attention for article published in Sao Paulo Medical Journal, September 2000
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Title
Vanishing bile duct syndrome in Hodgkin's disease: case report
Published in
Sao Paulo Medical Journal, September 2000
DOI 10.1590/s1516-31802000000500008
Pubmed ID
Authors

Marta Soares Rossini, Irene Lorand-Metze, Gislaine Borba Oliveira, Cármino Antonio De Souza

Abstract

Liver damage is relatively common in patients affected by Hodgkin's disease. A smaller proportion of cases develops jaundice. Recently, the vanishing bile duct syndrome was described in Hodgkin's disease. The mechanisms of this severe complication have been poorly understood until now. To describe a rare case of intra-hepatic cholestasis due to vanishing bile duct syndrome. Case report. A 38-year-old male patient affected by Hodgkin's disease. Liver biopsy showed no detectable Hodgkin's disease. Intra-hepatic cholestasis was found and none of the six portal tracts analyzed contained normal bile ducts. The treatment was based on conventional and high-dose escalation chemotherapy. The patient died from an irreversible liver failure while in complete remission from Hodgkin's disease.

Mendeley readers

Mendeley readers

The data shown below were compiled from readership statistics for 16 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
Japan 1 6%
Brazil 1 6%
Unknown 14 88%

Demographic breakdown

Readers by professional status Count As %
Other 6 38%
Student > Postgraduate 5 31%
Professor 1 6%
Student > Doctoral Student 1 6%
Researcher 1 6%
Other 1 6%
Unknown 1 6%
Readers by discipline Count As %
Medicine and Dentistry 15 94%
Unknown 1 6%