Title |
Applications of recombinant Pichia pastoris in the healthcare industry
|
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Published in |
Brazilian Journal of Microbiology, December 2013
|
DOI | 10.1590/s1517-83822013000400004 |
Pubmed ID | |
Authors |
Daniel Weinacker, Claudia Rabert, Andrea B. Zepeda, Carolina A. Figueroa, Adalberto Pessoa, Jorge G. Farías |
Abstract |
Since the 1970s, the establishment and development of the biotech industry has improved exponentially, allowing the commercial production of biopharmaceutical proteins. Nowadays, new recombinant protein production is considered a multibillion-dollar market, in which about 25% of commercial pharmaceuticals are biopharmaceuticals. But to achieve a competitive production process is not an easy task. Any production process has to be highly productive, efficient and economic. Despite that the perfect host is still not discovered, several research groups have chosen Pichia pastoris as expression system for the production of their protein because of its many features. The attempt of this review is to embrace several research lines that have adopted Pichia pastoris as their expression system to produce a protein on an industrial scale in the health care industry. |
X Demographics
Geographical breakdown
Country | Count | As % |
---|---|---|
Unknown | 1 | 100% |
Demographic breakdown
Type | Count | As % |
---|---|---|
Members of the public | 1 | 100% |
Mendeley readers
Geographical breakdown
Country | Count | As % |
---|---|---|
United Kingdom | 2 | <1% |
Spain | 2 | <1% |
India | 1 | <1% |
Austria | 1 | <1% |
Japan | 1 | <1% |
Unknown | 225 | 97% |
Demographic breakdown
Readers by professional status | Count | As % |
---|---|---|
Student > Bachelor | 50 | 22% |
Student > Master | 41 | 18% |
Student > Ph. D. Student | 39 | 17% |
Researcher | 18 | 8% |
Student > Doctoral Student | 14 | 6% |
Other | 26 | 11% |
Unknown | 44 | 19% |
Readers by discipline | Count | As % |
---|---|---|
Biochemistry, Genetics and Molecular Biology | 73 | 31% |
Agricultural and Biological Sciences | 63 | 27% |
Engineering | 15 | 6% |
Chemistry | 8 | 3% |
Immunology and Microbiology | 8 | 3% |
Other | 18 | 8% |
Unknown | 47 | 20% |