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Antifungal activity of metabolites of the endophytic fungus Trichoderma brevicompactum from garlic

Overview of attention for article published in Brazilian Journal of Microbiology, January 2014
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Title
Antifungal activity of metabolites of the endophytic fungus Trichoderma brevicompactum from garlic
Published in
Brazilian Journal of Microbiology, January 2014
DOI 10.1590/s1517-83822014005000036
Pubmed ID
Authors

Xuping Shentu, Xiaohuan Zhan, Zheng Ma, Xiaoping Yu, Chuanxi Zhang

Abstract

The endophytic fungus strain 0248, isolated from garlic, was identified as Trichoderma brevicompactum based on morphological characteristics and the nucleotide sequences of ITS1-5.8S- ITS2 and tef1. The bioactive compound T2 was isolated from the culture extracts of this fungus by bioactivity-guided fractionation and identified as 4β-acetoxy-12,13- epoxy-Δ(9)-trichothecene (trichodermin) by spectral analysis and mass spectrometry. Trichodermin has a marked inhibitory activity on Rhizoctonia solani, with an EC50 of 0.25 μgmL(-1). Strong inhibition by trichodermin was also found for Botrytis cinerea, with an EC50 of 2.02 μgmL(-1). However, a relatively poor inhibitory effect was observed for trichodermin against Colletotrichum lindemuthianum (EC50 = 25.60 μgmL(-1)). Compared with the positive control Carbendazim, trichodermin showed a strong antifungal activity on the above phytopathogens. There is little known about endophytes from garlic. This paper studied in detail the identification of endophytic T. brevicompactum from garlic and the characterization of its active metabolite trichodermin.

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Mendeley readers

Mendeley readers

The data shown below were compiled from readership statistics for 113 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
Unknown 113 100%

Demographic breakdown

Readers by professional status Count As %
Student > Bachelor 19 17%
Researcher 15 13%
Student > Ph. D. Student 14 12%
Student > Master 13 12%
Student > Doctoral Student 12 11%
Other 18 16%
Unknown 22 19%
Readers by discipline Count As %
Agricultural and Biological Sciences 42 37%
Biochemistry, Genetics and Molecular Biology 11 10%
Chemistry 9 8%
Immunology and Microbiology 4 4%
Pharmacology, Toxicology and Pharmaceutical Science 3 3%
Other 17 15%
Unknown 27 24%
Attention Score in Context

Attention Score in Context

This research output has an Altmetric Attention Score of 1. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 21 June 2014.
All research outputs
#22,759,802
of 25,374,647 outputs
Outputs from Brazilian Journal of Microbiology
#1,047
of 1,377 outputs
Outputs of similar age
#280,470
of 319,281 outputs
Outputs of similar age from Brazilian Journal of Microbiology
#21
of 40 outputs
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