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In vitro antagonistic activity of Lactobacillus casei against Helicobacter pylori

Overview of attention for article published in Brazilian Journal of Microbiology, December 2015
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  • High Attention Score compared to outputs of the same age and source (90th percentile)

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1 X user
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1 Wikipedia page

Citations

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14 Dimensions

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56 Mendeley
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Title
In vitro antagonistic activity of Lactobacillus casei against Helicobacter pylori
Published in
Brazilian Journal of Microbiology, December 2015
DOI 10.1590/s1517-838246420140675
Pubmed ID
Authors

Shymaa Enany, Salah Abdalla

Abstract

Helicobacter pylori is one of the most common causes of chronic infections in humans. Curing H. pylori infection is difficult because of the habitat of the organism below the mucus adherent layer of gastric mucosa. Lactobacilli are known as acid-resistant bacteria and can remain in stomach for a long time than any other organism, we aimed in this study to examine the efficacy of Lactobacillus casei as a probiotic against H. pylori in humans. Particularly, L. casei was opted as it is considered to be one of the widely used probiotics in dairy products. One hundred and seven strains of H. pylori were isolated from dyspeptic patients and were tested for their antibiotic susceptibility to metronidazole (MTZ), clarithromycin (CLR), tetracycline (TET), and amoxicillin (AMX) by the disc diffusion method. The strains were examined for their susceptibility toward L. casei - present in fermented milk products - by well diffusion method. It was found that 74.7% strains were resistant to MTZ; 1.8% to MTZ, TET, and CLR; 3.7% to MTZ and CLR; 4.6% to MTZ and TET; and 0.9% were resistant to MTZ, TET, and AMX. The antibacterial activity of L. casei against H. pylori was determined on all the tested H. pylori isolates including antibiotic resistant strains with different patterns. Our study proposed the use of probiotics for the treatment of H. pylori infection as an effective approach.

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X Demographics

The data shown below were collected from the profile of 1 X user who shared this research output. Click here to find out more about how the information was compiled.
Mendeley readers

Mendeley readers

The data shown below were compiled from readership statistics for 56 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
Unknown 56 100%

Demographic breakdown

Readers by professional status Count As %
Student > Master 8 14%
Student > Bachelor 7 13%
Other 4 7%
Lecturer 4 7%
Student > Postgraduate 3 5%
Other 13 23%
Unknown 17 30%
Readers by discipline Count As %
Medicine and Dentistry 10 18%
Agricultural and Biological Sciences 10 18%
Immunology and Microbiology 5 9%
Biochemistry, Genetics and Molecular Biology 3 5%
Pharmacology, Toxicology and Pharmaceutical Science 3 5%
Other 5 9%
Unknown 20 36%
Attention Score in Context

Attention Score in Context

This research output has an Altmetric Attention Score of 4. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 14 July 2020.
All research outputs
#7,960,512
of 25,374,647 outputs
Outputs from Brazilian Journal of Microbiology
#171
of 1,377 outputs
Outputs of similar age
#114,387
of 395,421 outputs
Outputs of similar age from Brazilian Journal of Microbiology
#2
of 20 outputs
Altmetric has tracked 25,374,647 research outputs across all sources so far. This one has received more attention than most of these and is in the 67th percentile.
So far Altmetric has tracked 1,377 research outputs from this source. They receive a mean Attention Score of 3.6. This one has done well, scoring higher than 86% of its peers.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 395,421 tracked outputs that were published within six weeks on either side of this one in any source. This one has gotten more attention than average, scoring higher than 70% of its contemporaries.
We're also able to compare this research output to 20 others from the same source and published within six weeks on either side of this one. This one has done particularly well, scoring higher than 90% of its contemporaries.