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Use of preoperative embolization prior to Transplant nephrectomy

Overview of attention for article published in International Brazilian Journal of Urology, January 2016
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Title
Use of preoperative embolization prior to Transplant nephrectomy
Published in
International Brazilian Journal of Urology, January 2016
DOI 10.1590/s1677-5538.ibju.2015.0052
Pubmed ID
Authors

Carrie Yeast, Julie M. Riley, Joshua Holyoak, Gilbert Ross, Stephen Weinstein, Mark Wakefield

Abstract

After a failed transplant, management of a non-functional graft with pain or recurrent infections can be challenging. Transplant nephrectomy (TN) can be a morbid procedure with the potential for significant blood loss. Embolization of the renal artery alone has been proposed as a method of reducing complications from an in vivo failed kidney transplant. While this does yield less morbidity, it may not address an infected graft or refractory hematuria or rejection. We elected to begin preoperative embolization to assess if this would help decrease the blood loss and transfusion rate associated with TN. We performed a retrospective analysis of all patients who underwent non-emergent TN at our institution. Patients who had functioning grafts that later failed were included in analysis. TN was performed for recurrent infections, pain or hematuria. We evaluated for blood loss (EBL) during TN, transfusion rate and length of hospital stay. A total of 16 patients were identified. Nine had preoperative embolization or no blood flow to the graft prior to TN. The remaining 7 did not have preoperative embolization. The shortest time from transplant to TN was 8 months and the longest 18 years with an average of 6.3 years. Average EBL for the embolized patients (ETN) was 143.9cc compared to 621.4cc in the non-embolized (NETN) group (p=0.041). Average number of units of blood transfused was 0.44 in the ETN with only 3/9 patients requiring transfusion. The NETN patients had average of 1.29 units transfused with 5/7 requiring transfusion. The length of stay was longer for the ETN (5.4 days) compared to 3.9 in the NETN. No intraoperative complications were seen in either group and only one patient had a postoperative ileus in the NETN. Embolization prior to TN significantly decreases the EBL but does not significantly decrease transfusion rate. However, patients do require a significantly longer hospitalization with embolization due to the time needed for embolization. Larger studies are needed to determine if embolization before transplant nephrectomy reduces the transfusion rates and overall complications.

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Mendeley readers

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Geographical breakdown

Country Count As %
Unknown 9 100%

Demographic breakdown

Readers by professional status Count As %
Student > Ph. D. Student 1 11%
Student > Bachelor 1 11%
Other 1 11%
Student > Postgraduate 1 11%
Unknown 5 56%
Readers by discipline Count As %
Medicine and Dentistry 3 33%
Biochemistry, Genetics and Molecular Biology 1 11%
Unknown 5 56%
Attention Score in Context

Attention Score in Context

This research output has an Altmetric Attention Score of 1. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 03 May 2016.
All research outputs
#22,759,802
of 25,374,917 outputs
Outputs from International Brazilian Journal of Urology
#624
of 726 outputs
Outputs of similar age
#341,819
of 399,677 outputs
Outputs of similar age from International Brazilian Journal of Urology
#51
of 58 outputs
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