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Vitamin C inhibits crystallization of struvite from artificial urine in the presence of Pseudomonas aeruginosa

Overview of attention for article published in International Brazilian Journal of Urology, December 2018
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Title
Vitamin C inhibits crystallization of struvite from artificial urine in the presence of Pseudomonas aeruginosa
Published in
International Brazilian Journal of Urology, December 2018
DOI 10.1590/s1677-5538.ibju.2017.0656
Pubmed ID
Authors

Muhammed A. P. Manzoor, Surya Ram Duwal, M. Mujeeburahiman, Punchappady-Devasya Rekha

Abstract

Formation of struvite stones is associated with urinary tract infection by urease-producing bacteria. Biogenic crystal growth in natural and synthetic materials is regulated by the action of inhibitors, ranging from small ions, molecules to large macromolecules. We report the dynamics of in vitro crystallization of struvite in presence of vitamin C in synthetic urine using single diffusion gel growth technique. Sodium metasilicate gel of specific gravity 1.05 and the aqueous solution of ammonium dihydrogen phosphate were used as the medium for growing the struvite crystals. The crystallization process was induced by a urease positive struvite stone associated Pseudomonas aeruginosa to mimic the infection leading to stone formation. The grown crystals were characterized by ATR-FTIR and powder XRD. The surface morphology was analysed through FE-SEM for comparison between treatments. We observed decrease in number, dimension, and growth rate of struvite crystals with the increasing concentrations of vitamin C. Crystals displayed well-defined faces and dendritic morphology of struvite in both control and biogenic systems. The results strongly suggest that, vitamin C can modulate the formation of struvite crystals in the presence of uropathogenic bacteria.

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Mendeley readers

Mendeley readers

The data shown below were compiled from readership statistics for 30 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
Unknown 30 100%

Demographic breakdown

Readers by professional status Count As %
Student > Master 5 17%
Student > Ph. D. Student 4 13%
Student > Bachelor 3 10%
Researcher 3 10%
Student > Doctoral Student 3 10%
Other 1 3%
Unknown 11 37%
Readers by discipline Count As %
Biochemistry, Genetics and Molecular Biology 4 13%
Veterinary Science and Veterinary Medicine 2 7%
Chemical Engineering 2 7%
Agricultural and Biological Sciences 2 7%
Medicine and Dentistry 2 7%
Other 5 17%
Unknown 13 43%
Attention Score in Context

Attention Score in Context

This research output has an Altmetric Attention Score of 1. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 05 April 2018.
All research outputs
#17,568,405
of 25,756,911 outputs
Outputs from International Brazilian Journal of Urology
#360
of 732 outputs
Outputs of similar age
#284,219
of 448,368 outputs
Outputs of similar age from International Brazilian Journal of Urology
#4
of 10 outputs
Altmetric has tracked 25,756,911 research outputs across all sources so far. This one is in the 21st percentile – i.e., 21% of other outputs scored the same or lower than it.
So far Altmetric has tracked 732 research outputs from this source. They receive a mean Attention Score of 4.4. This one is in the 38th percentile – i.e., 38% of its peers scored the same or lower than it.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 448,368 tracked outputs that were published within six weeks on either side of this one in any source. This one is in the 27th percentile – i.e., 27% of its contemporaries scored the same or lower than it.
We're also able to compare this research output to 10 others from the same source and published within six weeks on either side of this one. This one has scored higher than 6 of them.