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Trifecta achievement in patients undergoing partial nephrectomy: a systematic review and meta-analysis of predictive factors

Overview of attention for article published in International Brazilian Journal of Urology, August 2022
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Title
Trifecta achievement in patients undergoing partial nephrectomy: a systematic review and meta-analysis of predictive factors
Published in
International Brazilian Journal of Urology, August 2022
DOI 10.1590/s1677-5538.ibju.2021.0095
Pubmed ID
Authors

Nigemutu Bai, Muge Qi, Dan Shan, Suo Liu, Ta Na, Liang Chen

Abstract

The predictors of trifecta achievement in partial nephrectomy (PN) were poorly inquired and remained a controversial area of discovery. To evaluate predictive factors of trifecta achievement in patients undergoing PN. A systematic literature search was performed to identify relevant articles. Only studies focusing on postoperative trifecta achievement and exploring its predictor with multivariable analyses were included. The trifecta achievement was defined as negative surgical margins, warm ischemia time <25 minutes, and no complications. Merged odds ratio (OR) and 95% confidence interval (CI) were used to evaluate the predictive effect. Thirteen studies with 7066 patients meeting the inclusion criteria were included. The rate of trifecta achievement ranged from 43.3% to 78.6%. Merged results showed that preoperative eGFR (OR: 1.01, 95% CI: 1.00, 1.02, P=0.02), operative time (OR: 0.99, 95% CI: 0.99, 1.00, P=0.02), estimated blood loss (OR: 1.00, 95% CI: 1.00, 1.00, P <0.001), tumor size (OR: 0.70, 95% CI: 0.58, 0.84, P <0.001), medium (OR: 0.39, 95% CI: 0.18, 0.84, P=0.02) and high PADUA score (OR: 0.23, 95% CI: 0.08, 0.64, P=0.005) were independently associated with trifecta achievement. A publication bias was identified for tumor size. Sensitivity analysis confirmed the stability of result for tumor size. Larger tumor size, medium and high PADUA score are associated with decreased probability of trifecta achievement. After verifying by further high-quality studies, these variables can be incorporated into tools to predict probability of trifecta achievement during clinical practice.

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Mendeley readers

Mendeley readers

The data shown below were compiled from readership statistics for 13 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
Unknown 13 100%

Demographic breakdown

Readers by professional status Count As %
Other 2 15%
Student > Doctoral Student 1 8%
Student > Bachelor 1 8%
Student > Ph. D. Student 1 8%
Student > Master 1 8%
Other 2 15%
Unknown 5 38%
Readers by discipline Count As %
Medicine and Dentistry 2 15%
Biochemistry, Genetics and Molecular Biology 1 8%
Immunology and Microbiology 1 8%
Computer Science 1 8%
Psychology 1 8%
Other 1 8%
Unknown 6 46%
Attention Score in Context

Attention Score in Context

This research output has an Altmetric Attention Score of 1. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 12 June 2021.
All research outputs
#22,774,430
of 25,392,582 outputs
Outputs from International Brazilian Journal of Urology
#624
of 726 outputs
Outputs of similar age
#366,267
of 431,905 outputs
Outputs of similar age from International Brazilian Journal of Urology
#3
of 6 outputs
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