Title |
Molluscicidal effect of Euphorbia umbellata (Pax) Bruyns latex on Biomphalaria glabrata, Schistosoma mansoni host snail
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Published in |
Revista do Instituto de Medicina Tropical de Sao Paulo, December 2017
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DOI | 10.1590/s1678-9946201759085 |
Pubmed ID | |
Authors |
Luciana Patrícia Lima Alves Pereira, Clarice Noleto Dias, Milena Valadar Miranda, Wellyson da Cunha Araújo Firmo, Carliane dos Santos Rosa, Priscila Freitas Santos, Maria Cristiane Aranha Brito, Fernanda Oliveira Sousa Araruna, Felipe Bastos Araruna, Nêuton Silva-Souza, Denise Fernandes Coutinho |
Abstract |
Euphorbia umbellata (Pax) Bruyns is an easily cultivated shrub, with occurrence in the tropical regions of the American and African continents. Chemical studies have revealed that the latex of this plant is rich in terpene compounds, which are highly toxic to snails Biomphalaria glabrata (Basommatophora: Planorbidae). The aim of this study was to evaluate the chemical composition and molluscicidal activity of the latex produced by E. umbellata, as well as the safety of its application in aquatic environments. The concentration of latex that killed 90% of the exposed snails after 24 h exposure (LC90) was 3.69 mg/L. Toxicity bioassays using Danio rerio (zebrafish) revealed that these animals were less susceptible to latex than planorbids. However, it is important to perform other toxicity tests to ensure the feasibility of using latex to control populations of mollusks that contribute to schistosomiasis transmission. A phytochemical screening performed with the E. umbellata latex identified the triterpenoid and coumarin class. Further studies are warranted to isolate, identify, and test the active compounds of E. umbellata latex in B. glabrata. |
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United Kingdom | 1 | 50% |
Unknown | 1 | 50% |
Demographic breakdown
Type | Count | As % |
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Members of the public | 2 | 100% |
Mendeley readers
Geographical breakdown
Country | Count | As % |
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Unknown | 22 | 100% |
Demographic breakdown
Readers by professional status | Count | As % |
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Student > Master | 7 | 32% |
Student > Postgraduate | 2 | 9% |
Student > Ph. D. Student | 2 | 9% |
Student > Doctoral Student | 1 | 5% |
Researcher | 1 | 5% |
Other | 1 | 5% |
Unknown | 8 | 36% |
Readers by discipline | Count | As % |
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Agricultural and Biological Sciences | 6 | 27% |
Pharmacology, Toxicology and Pharmaceutical Science | 3 | 14% |
Nursing and Health Professions | 1 | 5% |
Immunology and Microbiology | 1 | 5% |
Earth and Planetary Sciences | 1 | 5% |
Other | 1 | 5% |
Unknown | 9 | 41% |