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Pathology and pathogenesis of human leptospirosis: a commented review

Overview of attention for article published in Revista do Instituto de Medicina Tropical de Sao Paulo, May 2018
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Title
Pathology and pathogenesis of human leptospirosis: a commented review
Published in
Revista do Instituto de Medicina Tropical de Sao Paulo, May 2018
DOI 10.1590/s1678-9946201860023
Pubmed ID
Authors

Thales De Brito, Ana Maria Gonçalves da Silva, Patrícia Antonia Estima Abreu

Abstract

Leptospirosis is an acute bacterial septicemic febrile disease caused by pathogenic leptospires, which affect humans and animals in all parts of the world. Transmission can occur by direct contact with infected animals or, more commonly, through indirect contact with water or soil contaminated with urine from infected animals. Leptospires enter the body by penetrating mucous membranes or skin abrasions and disseminate through the hematogenic route. In humans, leptospirosis may cause a wide spectrum of symptoms. Most cases have a biphasic clinical presentation, which begins with the septicemic phase followed by immune manifestations. The severe forms of the disease may be life threatening with multisystem damage including renal failure, hepatic dysfunction, vascular damage, pulmonary hemorrhage and muscle lesions. In this review, we present and discuss the pathogenesis of the human disease and the mechanisms of cell membrane injuries, which occur mainly due to the presence of leptospires and/or their antigen/s in the host tissues.

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The data shown below were collected from the profiles of 2 X users who shared this research output. Click here to find out more about how the information was compiled.
Mendeley readers

Mendeley readers

The data shown below were compiled from readership statistics for 277 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
Unknown 277 100%

Demographic breakdown

Readers by professional status Count As %
Student > Bachelor 67 24%
Student > Master 21 8%
Researcher 18 6%
Student > Doctoral Student 18 6%
Student > Ph. D. Student 15 5%
Other 44 16%
Unknown 94 34%
Readers by discipline Count As %
Medicine and Dentistry 78 28%
Biochemistry, Genetics and Molecular Biology 30 11%
Veterinary Science and Veterinary Medicine 21 8%
Immunology and Microbiology 7 3%
Unspecified 6 2%
Other 30 11%
Unknown 105 38%
Attention Score in Context

Attention Score in Context

This research output has an Altmetric Attention Score of 1. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 27 May 2021.
All research outputs
#20,663,600
of 25,382,440 outputs
Outputs from Revista do Instituto de Medicina Tropical de Sao Paulo
#565
of 785 outputs
Outputs of similar age
#268,499
of 344,432 outputs
Outputs of similar age from Revista do Instituto de Medicina Tropical de Sao Paulo
#5
of 6 outputs
Altmetric has tracked 25,382,440 research outputs across all sources so far. This one is in the 10th percentile – i.e., 10% of other outputs scored the same or lower than it.
So far Altmetric has tracked 785 research outputs from this source. They receive a mean Attention Score of 3.3. This one is in the 18th percentile – i.e., 18% of its peers scored the same or lower than it.
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We're also able to compare this research output to 6 others from the same source and published within six weeks on either side of this one.