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Assessment of adherence to the guidelines for the management of nausea and vomiting induced by chemotherapy

Overview of attention for article published in Einstein (São Paulo), January 2015
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Title
Assessment of adherence to the guidelines for the management of nausea and vomiting induced by chemotherapy
Published in
Einstein (São Paulo), January 2015
DOI 10.1590/s1679-45082015ao3097
Pubmed ID
Authors

Monique Sedlmaier França, Pedro Luiz Serrano Usón, Yuri Philippe Pimentel Vieira Antunes, Bernard Lobato Prado, Carlos del Cistia Donnarumma, Taciana Sousa Mutão, Heloisa Veasey Rodrigues, Auro del Giglio

Abstract

To assess adherence of the prescribing physicians in a private cancer care center to the American Society of Clinical Oncology guideline for antiemetic prophylaxis, in the first cycle of antineoplastic chemotherapy. A total of 139 chemotherapy regimens, of 105 patients, were evaluated retrospectively from 2011 to 2013. We observed 78% of non-adherence to the guideline rate. The main disagreements with the directive were the prescription of higher doses of dexamethasone and excessive use of 5-HT3 antagonist for low risk emetogenic chemotherapy regimens. On univariate analysis, hematological malignancies (p=0.005), the use of two or more chemotherapy (p=0.05) and high emetogenic risk regimes (p=0.012) were factors statistically associated with greater adherence to guidelines. Treatment based on paclitaxel was the only significant risk factor for non-adherence (p=0.02). By multivariate analysis, the chemotherapy of high emetogenic risk most correlated with adherence to guideline (p=0.05). We concluded that the adherence to guidelines is greater if the chemotherapy regime has high emetogenic risk. Educational efforts should focus more intensely on the management of chemotherapy regimens with low and moderate emetogenic potential. Perhaps the development of a computer generated reminder may improve the adherence to guidelines.

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Mendeley readers

Mendeley readers

The data shown below were compiled from readership statistics for 39 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
Unknown 39 100%

Demographic breakdown

Readers by professional status Count As %
Student > Bachelor 6 15%
Researcher 5 13%
Student > Master 5 13%
Professor 3 8%
Student > Postgraduate 3 8%
Other 6 15%
Unknown 11 28%
Readers by discipline Count As %
Medicine and Dentistry 12 31%
Nursing and Health Professions 8 21%
Pharmacology, Toxicology and Pharmaceutical Science 3 8%
Social Sciences 2 5%
Agricultural and Biological Sciences 1 3%
Other 2 5%
Unknown 11 28%
Attention Score in Context

Attention Score in Context

This research output has an Altmetric Attention Score of 1. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 21 October 2015.
All research outputs
#20,656,161
of 25,373,627 outputs
Outputs from Einstein (São Paulo)
#421
of 576 outputs
Outputs of similar age
#266,629
of 359,528 outputs
Outputs of similar age from Einstein (São Paulo)
#13
of 25 outputs
Altmetric has tracked 25,373,627 research outputs across all sources so far. This one is in the 10th percentile – i.e., 10% of other outputs scored the same or lower than it.
So far Altmetric has tracked 576 research outputs from this source. They typically receive a little more attention than average, with a mean Attention Score of 5.0. This one is in the 12th percentile – i.e., 12% of its peers scored the same or lower than it.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 359,528 tracked outputs that were published within six weeks on either side of this one in any source. This one is in the 14th percentile – i.e., 14% of its contemporaries scored the same or lower than it.
We're also able to compare this research output to 25 others from the same source and published within six weeks on either side of this one. This one is in the 24th percentile – i.e., 24% of its contemporaries scored the same or lower than it.