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Drogas antituberculose: interações medicamentosas, efeitos adversos e utilização em situações especiais - parte 1: fármacos de primeira linha

Overview of attention for article published in Jornal de Pneumologia, October 2010
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1 Facebook page

Citations

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174 Dimensions

Readers on

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382 Mendeley
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1 CiteULike
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Title
Drogas antituberculose: interações medicamentosas, efeitos adversos e utilização em situações especiais - parte 1: fármacos de primeira linha
Published in
Jornal de Pneumologia, October 2010
DOI 10.1590/s1806-37132010000500016
Pubmed ID
Authors

Marcos Abdo Arbex, Marília de Castro Lima Varella, Hélio Ribeiro de Siqueira, Fernando Augusto Fiúza de Mello

Abstract

The main objectives of tuberculosis therapy are to cure the patients and to minimize the possibility of transmission of the bacillus to healthy subjects. Adverse effects of antituberculosis drugs or drug interactions (among antituberculosis drugs or between antituberculosis drugs and other drugs) can make it necessary to modify or discontinue treatment. We briefly review the new guidelines for the pharmacological treatment of tuberculosis, introduced by the Brazilian National Ministry of Health in 2009, and describe the general mechanism of action, absorption, metabolization, and excretion of the first-line drugs used in the basic regimen. We describe adverse drug reactions and interactions (with other drugs, food, and antacids), as well as the most appropriate approach to special situations, such as pregnancy, breastfeeding, liver failure, and kidney failure. We also describe the mechanisms by which the interactions among the antituberculosis drugs used in the basic regimen can cause drug-induced hepatitis, and we discuss the alternatives in this situation.

Mendeley readers

Mendeley readers

The data shown below were compiled from readership statistics for 382 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
Brazil 2 <1%
Switzerland 1 <1%
India 1 <1%
Unknown 378 99%

Demographic breakdown

Readers by professional status Count As %
Student > Bachelor 67 18%
Student > Master 61 16%
Student > Ph. D. Student 43 11%
Student > Postgraduate 37 10%
Student > Doctoral Student 28 7%
Other 65 17%
Unknown 81 21%
Readers by discipline Count As %
Medicine and Dentistry 106 28%
Pharmacology, Toxicology and Pharmaceutical Science 60 16%
Biochemistry, Genetics and Molecular Biology 26 7%
Chemistry 25 7%
Agricultural and Biological Sciences 21 5%
Other 57 15%
Unknown 87 23%
Attention Score in Context

Attention Score in Context

This research output has an Altmetric Attention Score of 1. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 09 May 2014.
All research outputs
#22,830,981
of 25,457,858 outputs
Outputs from Jornal de Pneumologia
#556
of 719 outputs
Outputs of similar age
#103,219
of 108,896 outputs
Outputs of similar age from Jornal de Pneumologia
#5
of 5 outputs
Altmetric has tracked 25,457,858 research outputs across all sources so far. This one is in the 1st percentile – i.e., 1% of other outputs scored the same or lower than it.
So far Altmetric has tracked 719 research outputs from this source. They receive a mean Attention Score of 3.7. This one is in the 1st percentile – i.e., 1% of its peers scored the same or lower than it.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 108,896 tracked outputs that were published within six weeks on either side of this one in any source. This one is in the 1st percentile – i.e., 1% of its contemporaries scored the same or lower than it.
We're also able to compare this research output to 5 others from the same source and published within six weeks on either side of this one.