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Kinetics and avidity of anti-Toxocara antibodies (IgG) in rabbits experimentally infected with Toxocara canis

Overview of attention for article published in Revista Brasileira de Parasitologia Veterinária, November 2015
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Title
Kinetics and avidity of anti-Toxocara antibodies (IgG) in rabbits experimentally infected with Toxocara canis
Published in
Revista Brasileira de Parasitologia Veterinária, November 2015
DOI 10.1590/s1984-29612015067
Pubmed ID
Authors

Lundia Luara Cavalcante Bin, Vamilton Alvares Santarém, Cecília Braga Laposy, Guita Rubinsky-Elefant, William Henry Roldán, Rogério Giuffrida

Abstract

An evaluation was made of the kinetics and avidity of anti-Toxocara antibodies (IgG) in rabbits experimentally infected with embryonated Toxocara canis eggs. Seventeen four month old New Zealand White rabbits were distributed into two groups. In the experimental group, twelve rabbits were infected orally with 1,000 embryonated T. canis eggs. A second group (n = 5), uninfected, was used as a control. Serum samples were collected for analysis on days 7, 14, 21, 28 and 60 post-infection (DPI). An indirect ELISA test was performed to evaluate the reactivity index (RI) of IgG anti-T. canis antibodies and to calculate the avidity index (AI). The animals showed seroconversion from the 14th DPI, with high AI (over 50%) except for one animal, which presented an intermediate AI. At 60 DPI, all the animals were seropositive and maintained a high AI. The data indicated that specific IgG antibodies formed early (14 DPI) in rabbits infected with T. canis, with a high avidity index that persisted throughout the course of the infection.

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Attention Score in Context

This research output has an Altmetric Attention Score of 1. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 18 May 2018.
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#22,758,309
of 25,371,288 outputs
Outputs from Revista Brasileira de Parasitologia Veterinária
#432
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Outputs of similar age
#251,784
of 294,331 outputs
Outputs of similar age from Revista Brasileira de Parasitologia Veterinária
#9
of 12 outputs
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