Title |
Beta thalassemia major and pregnancy during adolescence: report of two cases
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Published in |
Revista Brasileira de Ginecologia e Obstetrícia, June 2015
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DOI | 10.1590/so100-720320150005169 |
Pubmed ID | |
Authors |
Lucas Augusto Monteiro Castro Trigo, Fernanda Garanhani Surita, Mary Angela Parpinelli, Belmiro Gonçalves Pereira, Kleber Yotsumoto Fertrin, Maria Laura Costa |
Abstract |
Beta thalassemia major is a rare hereditary blood disease in which impaired synthesis of beta globin chains causes severe anemia. Medical treatment consists of chronic blood transfusions and iron chelation. We describe two cases of adolescents with beta thalassemia major with unplanned pregnancies and late onset of prenatal care. One had worsening of anemia with increased transfusional requirement, fetal growth restriction, and placental senescence. The other was also diagnosed with hypothyroidism and low maternal weight, and was admitted twice during pregnancy due to dengue shock syndrome and influenza H1N1-associated respiratory infection. She also developed fetal growth restriction and underwent vaginal delivery at term complicated by uterine hypotonia. Both patients required blood transfusions after birth and chose medroxyprogesterone as a contraceptive method afterwards. This report highlights the importance of medical advice on contraceptive methods for these women and the role of a specialized prenatal follow-up in association with a hematologist. |
X Demographics
Geographical breakdown
Country | Count | As % |
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Unknown | 1 | 100% |
Demographic breakdown
Type | Count | As % |
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Members of the public | 1 | 100% |
Mendeley readers
Geographical breakdown
Country | Count | As % |
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Unknown | 35 | 100% |
Demographic breakdown
Readers by professional status | Count | As % |
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Student > Bachelor | 7 | 20% |
Researcher | 5 | 14% |
Student > Doctoral Student | 4 | 11% |
Student > Master | 4 | 11% |
Unspecified | 3 | 9% |
Other | 3 | 9% |
Unknown | 9 | 26% |
Readers by discipline | Count | As % |
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Medicine and Dentistry | 11 | 31% |
Nursing and Health Professions | 6 | 17% |
Unspecified | 3 | 9% |
Psychology | 2 | 6% |
Immunology and Microbiology | 1 | 3% |
Other | 2 | 6% |
Unknown | 10 | 29% |