Title |
Serious stomatitis and esophagitis: a peculiar mucous reaction induced by pegylated liposomal doxorubicin*
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Published in |
Anais Brasileiros de Dermatologia, January 2015
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DOI | 10.1590/abd1806-4841.20153708 |
Pubmed ID | |
Authors |
Han Ma, Meilan Chen, Junru Liu, Ying Li, Juan Li |
Abstract |
Pegylated liposomal doxorubicin is an important antineoplastic agent with activity in a variety of solid tumors. It has a totally different profile of pharmacokinetics and toxicity compared with doxorubicin. It rarely causes side-effects like cardiotoxicity or hair loss, but frequently results in many kinds of mucocutaneous reactions, including palmar-plantar erythrodysesthesia, diffuse follicular rash, intertrigo-like eruption, new formation of melanotic macules, stomatitis and radiation recall dermatitis. We present a rare case of multiple myeloma who immediately developed serious stomatitis and esophatitis associated with minor palmar-plantar erythrodysesthesia after a single course of pegylated liposomal doxorubicin. |
Mendeley readers
Geographical breakdown
Country | Count | As % |
---|---|---|
Unknown | 22 | 100% |
Demographic breakdown
Readers by professional status | Count | As % |
---|---|---|
Student > Bachelor | 3 | 14% |
Student > Master | 3 | 14% |
Student > Doctoral Student | 2 | 9% |
Other | 2 | 9% |
Student > Ph. D. Student | 2 | 9% |
Other | 3 | 14% |
Unknown | 7 | 32% |
Readers by discipline | Count | As % |
---|---|---|
Medicine and Dentistry | 7 | 32% |
Pharmacology, Toxicology and Pharmaceutical Science | 2 | 9% |
Nursing and Health Professions | 1 | 5% |
Environmental Science | 1 | 5% |
Economics, Econometrics and Finance | 1 | 5% |
Other | 3 | 14% |
Unknown | 7 | 32% |