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Paronychia and granulation tissue formation during treatment with isotretinoin*

Overview of attention for article published in Anais Brasileiros de Dermatologia, January 2016
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Title
Paronychia and granulation tissue formation during treatment with isotretinoin*
Published in
Anais Brasileiros de Dermatologia, January 2016
DOI 10.1590/abd1806-4841.20163817
Pubmed ID
Authors

Daniela de Almeida Figueiras, Ticiana Batista Ramos, Ayana Karla de Oliveira Ferreira Marinho, Milena Soneley Mendonça Bezerra, Renata Cavalcanti Cauas

Abstract

This paper describes the association of two unusual side effects of treatment with isotretinoin for severe acne: paronychia and excess granulation tissue in the nails furrows. We report a case of male patient aged 19 years, who in the course of the 36th week of treatment with isotretinoin for acne grade III showed erythema, edema, excess granulation tissue and onychocryptosis in various nail beds of hands and feet, with no history of trauma associated. A literature review revealed few reports of these adverse events, and two clinical patterns of exuberant granulation tissue has been described: one in periungual location and other in lesions of previous acne. The rarity and lack of knowledge on the best treatment for granuloma-like reactions make this theme a considerable challenge.

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Mendeley readers

Mendeley readers

The data shown below were compiled from readership statistics for 32 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
Brazil 1 3%
Unknown 31 97%

Demographic breakdown

Readers by professional status Count As %
Student > Bachelor 7 22%
Student > Master 4 13%
Student > Doctoral Student 3 9%
Researcher 2 6%
Student > Ph. D. Student 2 6%
Other 3 9%
Unknown 11 34%
Readers by discipline Count As %
Medicine and Dentistry 12 38%
Nursing and Health Professions 5 16%
Chemical Engineering 1 3%
Veterinary Science and Veterinary Medicine 1 3%
Pharmacology, Toxicology and Pharmaceutical Science 1 3%
Other 0 0%
Unknown 12 38%