Title |
Paronychia and granulation tissue formation during treatment with isotretinoin*
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Published in |
Anais Brasileiros de Dermatologia, January 2016
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DOI | 10.1590/abd1806-4841.20163817 |
Pubmed ID | |
Authors |
Daniela de Almeida Figueiras, Ticiana Batista Ramos, Ayana Karla de Oliveira Ferreira Marinho, Milena Soneley Mendonça Bezerra, Renata Cavalcanti Cauas |
Abstract |
This paper describes the association of two unusual side effects of treatment with isotretinoin for severe acne: paronychia and excess granulation tissue in the nails furrows. We report a case of male patient aged 19 years, who in the course of the 36th week of treatment with isotretinoin for acne grade III showed erythema, edema, excess granulation tissue and onychocryptosis in various nail beds of hands and feet, with no history of trauma associated. A literature review revealed few reports of these adverse events, and two clinical patterns of exuberant granulation tissue has been described: one in periungual location and other in lesions of previous acne. The rarity and lack of knowledge on the best treatment for granuloma-like reactions make this theme a considerable challenge. |
X Demographics
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Unknown | 1 | 100% |
Demographic breakdown
Type | Count | As % |
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Members of the public | 1 | 100% |
Mendeley readers
Geographical breakdown
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Brazil | 1 | 3% |
Unknown | 31 | 97% |
Demographic breakdown
Readers by professional status | Count | As % |
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Student > Bachelor | 7 | 22% |
Student > Master | 4 | 13% |
Student > Doctoral Student | 3 | 9% |
Researcher | 2 | 6% |
Student > Ph. D. Student | 2 | 6% |
Other | 3 | 9% |
Unknown | 11 | 34% |
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Chemical Engineering | 1 | 3% |
Veterinary Science and Veterinary Medicine | 1 | 3% |
Pharmacology, Toxicology and Pharmaceutical Science | 1 | 3% |
Other | 0 | 0% |
Unknown | 12 | 38% |