Title |
Orofacial granulomatosis and diet therapy: a review of the literature and two clinical cases*
|
---|---|
Published in |
Anais Brasileiros de Dermatologia, February 2018
|
DOI | 10.1590/abd1806-4841.20185828 |
Pubmed ID | |
Authors |
Iris Espinoza, Jorge Navarrete, Juana Benedetto, Arturo Borzutzky, Patricia Roessler, Ana Ortega-Pinto |
Abstract |
Orofacial granulomatosis is a nonspecific term that contains a wide variety of granulomatous entities, which share a clinical and histopathological presentation. It manifests as persistent or recurrent orofacial swelling, amongst other findings. Idiopathic orofacial granulomatosis, characterized by an absence of systemic granulomatous disease, is a diagnosis of exclusion. The main differential diagnosis is Crohn's disease. Its pathogenesis is unknown, however, it seems to be immune-mediated. Patch-test sensitivity to multiple allergens is well documented. Currently, therapeutic options consider restrictive diets, topical, intralesional, and systemic agents. First-line therapy is currently a matter of debate. We present a review of the value of diet therapy in this syndrome, along with two illustrative cases. |
X Demographics
Geographical breakdown
Country | Count | As % |
---|---|---|
United Kingdom | 1 | 25% |
United States | 1 | 25% |
Australia | 1 | 25% |
Unknown | 1 | 25% |
Demographic breakdown
Type | Count | As % |
---|---|---|
Practitioners (doctors, other healthcare professionals) | 2 | 50% |
Members of the public | 1 | 25% |
Scientists | 1 | 25% |
Mendeley readers
Geographical breakdown
Country | Count | As % |
---|---|---|
Unknown | 19 | 100% |
Demographic breakdown
Readers by professional status | Count | As % |
---|---|---|
Student > Bachelor | 6 | 32% |
Student > Ph. D. Student | 2 | 11% |
Student > Doctoral Student | 2 | 11% |
Other | 1 | 5% |
Professor > Associate Professor | 1 | 5% |
Other | 1 | 5% |
Unknown | 6 | 32% |
Readers by discipline | Count | As % |
---|---|---|
Medicine and Dentistry | 11 | 58% |
Nursing and Health Professions | 3 | 16% |
Engineering | 1 | 5% |
Unknown | 4 | 21% |