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Effect of different commercial fat sources on brain, liver and blood lipid profiles of rats in growth phase 1

Overview of attention for article published in Acta Cirúrgica Brasileira, December 2017
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Title
Effect of different commercial fat sources on brain, liver and blood lipid profiles of rats in growth phase 1
Published in
Acta Cirúrgica Brasileira, December 2017
DOI 10.1590/s0102-865020170120000003
Pubmed ID
Authors

Michel Cardoso de Angelis-Pereira, Maria de Fátima Píccolo Barcelos, Juciane de Abreu Ribeiro Pereira, Rafaela Corrêa Pereira, Raimundo Vicente de Souza

Abstract

To investigate the fatty acid content of different fat sources and evaluate the effect of them on plasma and hepatic lipids and on the fatty acid profile of the brain tissue of Wistar rats. Thirty male albino Wistar rats received for 59 days, the following diets: diet added of margarine with low content of polyunsaturated fatty acids (PUFA); diet added of margarine with high content of PUFA; diet added of butter; diet added of hydrogenated vegetable fat; diet added of soybean oil. Fatty acid profile of the lipid sources, blood and hepatic lipids fractions and fatty acid profile of the brain tissue were determined. Margarine consumption of provided different responses as to concentrations of blood and hepatic lipid fractions. Intake of butter and hydrogenated increased LDL-c/HDL-c ratio, being the steepest increase promoted by hydrogenated vegetable fat, which also raised LDL-c levels expressively. All fats used in the treatments reduced the cerebral concentration of docosahexaenoic acid when compared to soybean oil (control). The different fat sources commonly consumed by population provided different responses in vivo. This is particularly relevant considering the role of these lipids in the incidence and prevention of cardiovascular diseases.

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The data shown below were compiled from readership statistics for 26 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
Unknown 26 100%

Demographic breakdown

Readers by professional status Count As %
Student > Bachelor 5 19%
Student > Master 4 15%
Other 3 12%
Student > Ph. D. Student 2 8%
Student > Doctoral Student 1 4%
Other 3 12%
Unknown 8 31%
Readers by discipline Count As %
Medicine and Dentistry 7 27%
Biochemistry, Genetics and Molecular Biology 4 15%
Nursing and Health Professions 4 15%
Agricultural and Biological Sciences 1 4%
Unknown 10 38%