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Ten cases with 46,XX testicular disorder of sex development: single center experience

Overview of attention for article published in International Brazilian Journal of Urology, January 2017
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Title
Ten cases with 46,XX testicular disorder of sex development: single center experience
Published in
International Brazilian Journal of Urology, January 2017
DOI 10.1590/s1677-5538.ibju.2016.0505
Pubmed ID
Authors

Emre Can Akinsal, Numan Baydilli, Abdullah Demirtas, Cetin Saatci, Oguz Ekmekcioglu

Abstract

To present clinical, chromosomal and hormonal features of ten cases with SRY-positive 46,XX testicular disorder of sex development who were admitted to our infertility clinic. Records of the cases who were admitted to our infertility clinic between 2004 and 2015 were investigated. Ten 46,XX testicular disorder of sex development cases were detected. Clinical, hormonal and chromosomal assessments were analized. Mean age at diagnosis was 30.4, mean body height was 166.9cm. Hormonal data indicated that the patients had a higher FSH, LH levels, lower TT level and normal E2, PRL levels. Karyotype analysis of all patients confirmed 46,XX karyotype, and FISH analysis showed that SRY gene was positive and translocated to Xp. The AZFa, AZFb and AZFc regions were absent in 8 cases. In one case AZFb and AZFc incomplete deletion and normal AZFa region was present. In the other one all AZF regions were present. Gonadal development disorders such as SRY-positive 46,XX testicular disorder of sex development can be diagnosed in infertility clinics during infertility workup. Although these cases had no chance of bearing a child, they should be protected from negative effects of testosterone deficiency by replacement therapies.

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Mendeley readers

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The data shown below were compiled from readership statistics for 21 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
Unknown 21 100%

Demographic breakdown

Readers by professional status Count As %
Student > Bachelor 4 19%
Student > Ph. D. Student 3 14%
Student > Master 2 10%
Researcher 2 10%
Professor 1 5%
Other 1 5%
Unknown 8 38%
Readers by discipline Count As %
Biochemistry, Genetics and Molecular Biology 4 19%
Medicine and Dentistry 4 19%
Agricultural and Biological Sciences 1 5%
Psychology 1 5%
Chemistry 1 5%
Other 0 0%
Unknown 10 48%
Attention Score in Context

Attention Score in Context

This research output has an Altmetric Attention Score of 1. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 06 April 2017.
All research outputs
#20,660,571
of 25,382,440 outputs
Outputs from International Brazilian Journal of Urology
#469
of 726 outputs
Outputs of similar age
#320,195
of 421,709 outputs
Outputs of similar age from International Brazilian Journal of Urology
#27
of 47 outputs
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We're also able to compare this research output to 47 others from the same source and published within six weeks on either side of this one. This one is in the 10th percentile – i.e., 10% of its contemporaries scored the same or lower than it.