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Identification and antifungal susceptibility of Candida species isolated from the urine of patients in a university hospital in Brazil

Overview of attention for article published in Revista do Instituto de Medicina Tropical de Sao Paulo, December 2017
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Title
Identification and antifungal susceptibility of Candida species isolated from the urine of patients in a university hospital in Brazil
Published in
Revista do Instituto de Medicina Tropical de Sao Paulo, December 2017
DOI 10.1590/s1678-9946201759075
Pubmed ID
Authors

Gláucia Moreira Espíndola Lima, Maína de Oliveira Nunes, Marilene Rodrigues Chang, Rosianne Assis de Sousa Tsujisaki, Joslaine de Oliveira Nunes, Cleison Ledesma Taira, Danilo Yamamoto Thomaz, Gilda Maria Bárbaro Del Negro, Rinaldo Pôncio Mendes, Anamaria Mello Miranda Paniago

Abstract

The aim of this study was to identify Candida spp. isolated from candiduria episodes at a tertiary hospital in the Midwest region of Brazil, and to determine their susceptibility profiles to antifungal compounds. From May 2011 to April 2012, Candida spp. isolated from 106 adult patients with candiduria admitted to the University Hospital of the Federal University of Mato Grosso do Sul were evaluated. Both, species identification and susceptibility testing with fluconazole-FLC, voriconazole-VRC, and amphotericin B-AmB were carried out using the Vitek 2. To discriminate species of the C. parapsilosis complex, a RAPD-PCR technique using the RPO2 primer was performed. From the total of 106 isolates, 42 (39.6%) C. albicans and 64 (60.4%) Candida non-albicans (CNA) - 33 C. tropicalis, 18 C. glabrata, 5 C. krusei, 4 C. parapsilosis sensu stricto, 2 C. kefyr, 1 C. lusitaniae, and 1 C. guilliermondii were identified. All isolates were susceptible to AmB and VRC, whereas all C. glabrata isolates presented either resistance (5.6%) or dose-dependent susceptibility (94.4%) to FLC. The study of Candida spp. and their resistance profiles may help in tailoring more efficient therapeutic strategies for candiduria.

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Mendeley readers

Mendeley readers

The data shown below were compiled from readership statistics for 51 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
Unknown 51 100%

Demographic breakdown

Readers by professional status Count As %
Student > Bachelor 6 12%
Student > Ph. D. Student 5 10%
Student > Postgraduate 5 10%
Other 2 4%
Professor > Associate Professor 2 4%
Other 7 14%
Unknown 24 47%
Readers by discipline Count As %
Medicine and Dentistry 5 10%
Pharmacology, Toxicology and Pharmaceutical Science 5 10%
Immunology and Microbiology 4 8%
Biochemistry, Genetics and Molecular Biology 3 6%
Nursing and Health Professions 3 6%
Other 4 8%
Unknown 27 53%
Attention Score in Context

Attention Score in Context

This research output has an Altmetric Attention Score of 1. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 29 March 2018.
All research outputs
#22,764,772
of 25,382,440 outputs
Outputs from Revista do Instituto de Medicina Tropical de Sao Paulo
#643
of 785 outputs
Outputs of similar age
#387,416
of 447,689 outputs
Outputs of similar age from Revista do Instituto de Medicina Tropical de Sao Paulo
#8
of 15 outputs
Altmetric has tracked 25,382,440 research outputs across all sources so far. This one is in the 1st percentile – i.e., 1% of other outputs scored the same or lower than it.
So far Altmetric has tracked 785 research outputs from this source. They receive a mean Attention Score of 3.3. This one is in the 1st percentile – i.e., 1% of its peers scored the same or lower than it.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 447,689 tracked outputs that were published within six weeks on either side of this one in any source. This one is in the 1st percentile – i.e., 1% of its contemporaries scored the same or lower than it.
We're also able to compare this research output to 15 others from the same source and published within six weeks on either side of this one. This one is in the 1st percentile – i.e., 1% of its contemporaries scored the same or lower than it.