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Mendeley readers
Attention Score in Context
| Title |
Inflammatory cytokines in leprosy reactions and periodontal diseases
|
|---|---|
| Published in |
Revista do Instituto de Medicina Tropical de Sao Paulo, November 2018
|
| DOI | 10.1590/s1678-9946201860068 |
| Pubmed ID | |
| Authors |
Denise Costa Boamorte Cortela, Maria Renata Sales Nogueira, Ana Carla Pereira, Alcione Lescano de Souza, Eliane Ignotti |
| Abstract |
The inflammatory cytokines involved in the immune response to chronic periodontal disease (CPD) in the context of leprosy reactions (LR) were analyzed in 57 new cases of multibacillary leprosy (MBL). They were stratified by the presence of CPD and LR. Messenger RNA (mRNA) expression of inflammatory mediators was determined by qRT-PCR using skin biopsy and by ELISA using serum samples, maintaining 5% of significance level in ANOVA and correlation analyses. Twenty-three (40.4%) patients presented the first LR, whereas 22 (45.0%) patients presented CPD. IL-4 and IL-6 serum levels were significantly lower in patients with CPD and LR than in patients without CPD but with LR; IFN-γ serum levels were higher in patients with CPD and LR than in patients with no CPD and no LR; IL-4 serum levels were negatively correlated with TNF-α gene expression, while IL-6 serum levels were positively correlated with IFN-γ gene expression, in the skin of subjects with CPD and LR. The presence of DPC in individuals with LR immunoregulated IL-6, IFN-γ, and IL-4 concentrations. The presence of DPC decreased serum levels of IL-6 and IL-4 in reactional individuals. CPD concomitant to LR resulted in increased IFN-γ serum levels. |
X Demographics
The data shown below were collected from the profile of 1 X user who shared this research output. Click here to find out more about how the information was compiled.
Geographical breakdown
| Country | Count | As % |
|---|---|---|
| Netherlands | 1 | 100% |
Demographic breakdown
| Type | Count | As % |
|---|---|---|
| Members of the public | 1 | 100% |
Mendeley readers
The data shown below were compiled from readership statistics for 26 Mendeley readers of this research output. Click here to see the associated Mendeley record.
Geographical breakdown
| Country | Count | As % |
|---|---|---|
| Unknown | 26 | 100% |
Demographic breakdown
| Readers by professional status | Count | As % |
|---|---|---|
| Researcher | 3 | 12% |
| Student > Doctoral Student | 3 | 12% |
| Student > Postgraduate | 3 | 12% |
| Student > Master | 3 | 12% |
| Other | 2 | 8% |
| Other | 4 | 15% |
| Unknown | 8 | 31% |
| Readers by discipline | Count | As % |
|---|---|---|
| Medicine and Dentistry | 14 | 54% |
| Nursing and Health Professions | 2 | 8% |
| Biochemistry, Genetics and Molecular Biology | 2 | 8% |
| Unknown | 8 | 31% |
Attention Score in Context
This research output has an Altmetric Attention Score of 1. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 16 November 2018.
All research outputs
#20,027,150
of 25,477,125 outputs
Outputs from Revista do Instituto de Medicina Tropical de Sao Paulo
#530
of 786 outputs
Outputs of similar age
#269,154
of 365,279 outputs
Outputs of similar age from Revista do Instituto de Medicina Tropical de Sao Paulo
#13
of 18 outputs
Altmetric has tracked 25,477,125 research outputs across all sources so far. This one is in the 18th percentile – i.e., 18% of other outputs scored the same or lower than it.
So far Altmetric has tracked 786 research outputs from this source. They receive a mean Attention Score of 3.3. This one is in the 28th percentile – i.e., 28% of its peers scored the same or lower than it.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 365,279 tracked outputs that were published within six weeks on either side of this one in any source. This one is in the 21st percentile – i.e., 21% of its contemporaries scored the same or lower than it.
We're also able to compare this research output to 18 others from the same source and published within six weeks on either side of this one. This one is in the 22nd percentile – i.e., 22% of its contemporaries scored the same or lower than it.