Title |
Autologous stem-cell transplantation for multiple myeloma: a Brazilian institution experience in 15 years of follow-up
|
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Published in |
Einstein (São Paulo), June 2011
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DOI | 10.1590/s1679-45082011ao1845 |
Pubmed ID | |
Authors |
Juliana Todaro, Ana Rita de Araújo Burgos Manhani, José Mauro Kutner, Andreza Alice Feitosa Ribeiro, Morgani Rodrigues, Fabio Rodrigues Kerbauy, Jairo Nascimento Sobrinho, Eurípedes Ferreira, Nelson Hamerschlak |
Abstract |
To determine the 5-year post-transplant survival of patients with multiple myeloma. A retrospective study in patients diagnosed with multiple myeloma submitted to autologous bone marrow transplantation at a Brazilian institution, during the period of 1993 to 2007. Seventy-three patients were evaluated with a median age of 55 years. Survival in 5 years was 75% (2.4 to 60 months). Statistical analysis demonstrated statistical significance for the applied grade of response prior to treatment with autologous bone marrow transplantation (p = 0.01). There was no statistical significance for clinical staging or time of diagnosis (before or after the year 2000). Experience in autologous bone marrow transplantation for multiple myeloma at a Brazilian institution demonstrated an evolution consistent with that of medical literature and highlighted the importance of a response to treatment prior to transplantation in the survival of these patients. |
Mendeley readers
Geographical breakdown
Country | Count | As % |
---|---|---|
United Kingdom | 1 | 6% |
Unknown | 15 | 94% |
Demographic breakdown
Readers by professional status | Count | As % |
---|---|---|
Student > Bachelor | 7 | 44% |
Student > Postgraduate | 2 | 13% |
Other | 1 | 6% |
Researcher | 1 | 6% |
Student > Ph. D. Student | 1 | 6% |
Other | 0 | 0% |
Unknown | 4 | 25% |
Readers by discipline | Count | As % |
---|---|---|
Medicine and Dentistry | 4 | 25% |
Pharmacology, Toxicology and Pharmaceutical Science | 2 | 13% |
Biochemistry, Genetics and Molecular Biology | 1 | 6% |
Immunology and Microbiology | 1 | 6% |
Agricultural and Biological Sciences | 1 | 6% |
Other | 2 | 13% |
Unknown | 5 | 31% |