Title |
Immunohaematological and rheological parameters in canine visceral leishmaniasis
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Published in |
Revista Brasileira de Parasitologia Veterinária, May 2018
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DOI | 10.1590/s1984-296120180021 |
Pubmed ID | |
Authors |
José Nivaldo da Silva, Aron Carlos Cotrim, Luciana Auxiliadora Viebrantz da Conceição, Camila Moreira Ferreira Marins, Patricia Gelli Feres de Marchi, Adenilda Cristina Honorio-França, Arleana do Bom Parto Ferreira de Almeida, Eduardo Luzía França, Valéria Régia Franco Sousa |
Abstract |
The aim of this study was to find correlations between haematological and rheological parameters in canine visceral leishmaniasis (CLV). Enrolled dogs with CVL (n=31) had a confirmed diagnosis using the rapid test Dual Path Platform (TR DPP®) kit and Polymerase Chain Reaction (PCR) assay. A control group (n=31) comprised healthy dogs with negative results for the TR DPP® kit and PCR assay. Haematological parameters and total protein, albumin, globulin, and antibody were assessed. The rheological properties of the blood samples were also determined. Erythrocytes, haematocrit and platelet values of dogs in the CVL group were found to be lower than those of the control group. The total protein, globulin and IgG concentrations were higher in serum samples from the CVL group. The blood flow curve demonstrated increased shear rates in the CVL group. The viscosity of the blood from the infected animals was lower than in the healthy dogs. A positive correlation was found between erythrocyte numbers and blood viscosity. These data suggest that changes in the flow curve and viscosity of blood as well as the erythrocyte values may be a viable low-cost alternative for the monitoring of dogs with visceral leishmaniasis. |
X Demographics
Geographical breakdown
Country | Count | As % |
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Unknown | 2 | 100% |
Demographic breakdown
Type | Count | As % |
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Members of the public | 2 | 100% |
Mendeley readers
Geographical breakdown
Country | Count | As % |
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Unknown | 20 | 100% |
Demographic breakdown
Readers by professional status | Count | As % |
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Student > Doctoral Student | 3 | 15% |
Student > Bachelor | 3 | 15% |
Student > Ph. D. Student | 1 | 5% |
Student > Master | 1 | 5% |
Researcher | 1 | 5% |
Other | 1 | 5% |
Unknown | 10 | 50% |
Readers by discipline | Count | As % |
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Veterinary Science and Veterinary Medicine | 4 | 20% |
Medicine and Dentistry | 3 | 15% |
Pharmacology, Toxicology and Pharmaceutical Science | 1 | 5% |
Agricultural and Biological Sciences | 1 | 5% |
Design | 1 | 5% |
Other | 0 | 0% |
Unknown | 10 | 50% |