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Microbiological and therapeutic characteristics of confirmed neonatal sepsis at a hospital in Lima, Peru.

Overview of attention for article published in Revista Peruana de Medicina Experimental y Salud Pública, March 2016
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Title
Microbiological and therapeutic characteristics of confirmed neonatal sepsis at a hospital in Lima, Peru.
Published in
Revista Peruana de Medicina Experimental y Salud Pública, March 2016
DOI 10.17843/rpmesp.2016.331.2010
Pubmed ID
Authors

Giancarlo Alvarado-Gamarra, Katherine M Alcalá-Marcos, Diego M Abarca-Alfaro, Victoria Bao-Castro

Abstract

To describe the microbiological and therapeutic characteristics of confirmed neonatal sepsis, and determineits incidence and mortality, at the National Hospital Arzobispo Loayza (HNAL) from 2011 to 2012, Lima, Peru. Retrospective longitudinal study. It was performed a monitoring to newborns with probable sepsis, and assessed the results from positive blood cultures. The newborns' characteristics were obtained from medical records. The acumulated incidences of confirmed sepsis, mortality and fatality rates were determined. Quantitative variables were reported as men ± standard deviation or median (interquartile range). Qualitative variables were reported as relative frequencies and percentages. The incidence of confirmed sepsis was 4.1 per 1 000 live births (95% confidence interval [CI]: 2.7-5.5). The mortality rate was 0.97 per 1 000 live births (95% CI: 0.29-1.63) and the fatality rate was 23.5% (95% CI: 9-37). The most commonly isolated organism was coagulase-negative Staphylococcus, followed by Staphylococcus aureus, both with high rates of oxacillin resistance (90% and 66.6%, respectively). A 67% of the newborns were treated using ampicillin/amikacin or ampicillin/cefotaxime. Antibiotics were changed in 58% of the newborns because of poor clinical/laboratory evolution or blood culture results. In most cases the seconds antibiotic was vancomycin (42.8%). There is a high incidence of confirmed sepsis and a high fatality rate. The administered treatments were not consistent with the microbiological profiles.

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Mendeley readers

Mendeley readers

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Geographical breakdown

Country Count As %
Unknown 53 100%

Demographic breakdown

Readers by professional status Count As %
Student > Bachelor 10 19%
Student > Master 7 13%
Researcher 4 8%
Student > Doctoral Student 3 6%
Other 2 4%
Other 7 13%
Unknown 20 38%
Readers by discipline Count As %
Medicine and Dentistry 15 28%
Pharmacology, Toxicology and Pharmaceutical Science 5 9%
Nursing and Health Professions 4 8%
Biochemistry, Genetics and Molecular Biology 3 6%
Mathematics 1 2%
Other 6 11%
Unknown 19 36%
Attention Score in Context

Attention Score in Context

This research output has an Altmetric Attention Score of 1. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 08 July 2016.
All research outputs
#22,760,732
of 25,377,790 outputs
Outputs from Revista Peruana de Medicina Experimental y Salud Pública
#370
of 458 outputs
Outputs of similar age
#271,908
of 314,790 outputs
Outputs of similar age from Revista Peruana de Medicina Experimental y Salud Pública
#5
of 6 outputs
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So far Altmetric has tracked 458 research outputs from this source. They receive a mean Attention Score of 2.4. This one is in the 1st percentile – i.e., 1% of its peers scored the same or lower than it.
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