Title |
Hyperferritinemic sepsis secondary to invasive <i>Toxoplasma gondii</i> in a child with untreated HIV
|
---|---|
Published in |
Boletín Médico del Hospital Infantil de México, July 2023
|
DOI | 10.24875/bmhim.22000051 |
Pubmed ID | |
Authors |
Jesús Domínguez-Rojas, Jackeline Caute-Lara, Patrick Caqui-Vilca, Mario Cruz-Arpi, Carlos Martel-Ramírez, Miguel Quispe-Chipana, Abel Sánchez-Rodríguez, Noé Atamari-Anahui |
Abstract |
Untreated human immunodeficiency virus (HIV)-immunosuppressed pediatric patients show high morbidity and mortality from opportunistic infections. Limited cases of hyperferritinemic sepsis have been described in patients with toxoplasmosis. We describe the case of a 13-year-old female patient with a history of untreated HIV who presented with hyperferritinemic sepsis secondary to Toxoplasma gondii infection and Pneumocystis jirovecci pneumonia. She received ventilatory support, inotropic drugs, treatment for opportunistic germs, and high-dose corticosteroids, but with unfavorable evolution. The global approach to sepsis with elevated ferritin guides to using of therapies aimed at neutralizing the severe inflammatory response. A timely diagnosis would allow prompt treatment and minimize complications. |
X Demographics
Geographical breakdown
Country | Count | As % |
---|---|---|
United States | 1 | 50% |
Unknown | 1 | 50% |
Demographic breakdown
Type | Count | As % |
---|---|---|
Members of the public | 2 | 100% |