Title |
HELICOBACTER PYLORI (HP) INFECTION IN OBESE PATIENTS UNDERGOING ROUXEN- Y GASTRIC BYPASS; EFFICACY OF TWO DIFFERENT TREATMENT REGIMENS IN HP ERADICATION.
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Published in |
Nutrición Hospitalaria, August 2015
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DOI | 10.3305/nh.2015.32.2.9177 |
Pubmed ID | |
Authors |
Martín Cuesta Hernández, Celia Pérez Peña, Pilar Matía Martín, Lucio Cabrerizo García, Natalia Pérez-Ferre, Andrés Sánchez-Pernaute, Antonio Torres García, Miguel Ángel Rubio Herrera |
Abstract |
the ultimate cause for the increased incidence of gastric ulcer following Roux-en-Y gastric bypass (RYGB) remains unclear. Treatment of HP infection is recommended before surgery in countries with high prevalence such as Spain in other to diminish the risk. However, the current regimens used might not be adequate in view of the high failure rate for HP eradication. we reviewed 243 patients retrospectively undergoing RYGB and found 111 patients (45%) with HP infection. Therefore, we compared the eradication rate between 2 different regimens. 70 patients received OCA(Omeprazole:20 mg/12h, Clarithromycin 500 mg/12h and Amoxicillin 1 gram/12h for 10 days) while 41 patients received OLA (Omeprazole 20 mg/12 hours, Levofloxacin 500 mg/12hours and Amoxicillin 1 gram/12h for 10 days) for HP eradication. In 56/70 (80%) patients receiving OCA therapy HP was eradicated compared to 37/41 (91%) receiving OLA as first line therapy (p = 0.283). When used as second line therapy, in 13/14 (92%) patients receiving OLA HP was eradicated. clarithromycin resistance remains a matter of concern in this population while OLA seems to be a good alternative therapy for HP eradication, especially when OCA regimen fails. |
X Demographics
Geographical breakdown
Country | Count | As % |
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United States | 1 | 100% |
Demographic breakdown
Type | Count | As % |
---|---|---|
Practitioners (doctors, other healthcare professionals) | 1 | 100% |
Mendeley readers
Geographical breakdown
Country | Count | As % |
---|---|---|
Unknown | 30 | 100% |
Demographic breakdown
Readers by professional status | Count | As % |
---|---|---|
Student > Bachelor | 9 | 30% |
Researcher | 4 | 13% |
Student > Master | 3 | 10% |
Student > Ph. D. Student | 2 | 7% |
Lecturer > Senior Lecturer | 1 | 3% |
Other | 2 | 7% |
Unknown | 9 | 30% |
Readers by discipline | Count | As % |
---|---|---|
Medicine and Dentistry | 11 | 37% |
Immunology and Microbiology | 3 | 10% |
Nursing and Health Professions | 2 | 7% |
Environmental Science | 1 | 3% |
Pharmacology, Toxicology and Pharmaceutical Science | 1 | 3% |
Other | 1 | 3% |
Unknown | 11 | 37% |