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PREVALENCE OF AUTOIMMUNE THYROIDITIS AND THYROID DYSFUNCTION IN HEALTHY ADULT MEXICANS WITH A SLIGHTLY EXCESSIVE IODINE INTAKE.

Overview of attention for article published in Nutrición Hospitalaria, August 2015
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Title
PREVALENCE OF AUTOIMMUNE THYROIDITIS AND THYROID DYSFUNCTION IN HEALTHY ADULT MEXICANS WITH A SLIGHTLY EXCESSIVE IODINE INTAKE.
Published in
Nutrición Hospitalaria, August 2015
DOI 10.3305/nh.2015.32.2.9246
Pubmed ID
Authors

Armando Flores-Rebollar, Lidia Moreno-Castañeda, Norman S Vega-Servín, Guadalupe López-Carrasco, Aída Ruiz-Juvera

Abstract

the purpose of this study was to evaluate the prevalence of autoimmune thyroiditis and thyroid dysfunction in healthy individuals with no previously known thyroid disease, in an urban area of Mexico City. the study was conducted on volunteers with no known thyroid disease. We recruited 427 subjects among the hospital's medical and administration personnel. All underwent thyroid ultrasound (US) and TSH, free T4 (FT4), total T3 (TT3), thyroid anti-peroxidase (TPOAb) and anti-thyroglobulin (TgAb) antibodies were measured. Hypoechogenicity and thyroid volume were determined by US. Urinary iodine (UI) excretion was also measured. the frequency of autoimmune thyroiditis was 8.4% (36/427) and women were most commonly affected than men (11.6 vs. 4.3% respectively, P = 0.008); when including cases of atrophic thyroid, the frequency increased to 15.7% (67/427). Clinical hypothyroidism was detected in 1.2% (5/427) and it was sub-clinical in 5.6% of individuals. A goiter was present in 5.9% (25/427) of volunteers. Median UI was 267 μg/L, (IQR 161.3 - 482.5). in spite of our study's limitations, the frequency of autoimmune thyroiditis is clearly elevated in the studied population. Further studies are necessary in order to define the prevalence of autoimmune thyroid disease as well as the current iodine nutritional status in our country.

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Geographical breakdown

Country Count As %
Unknown 56 100%

Demographic breakdown

Readers by professional status Count As %
Student > Postgraduate 9 16%
Student > Ph. D. Student 6 11%
Student > Master 6 11%
Student > Doctoral Student 5 9%
Student > Bachelor 5 9%
Other 8 14%
Unknown 17 30%
Readers by discipline Count As %
Medicine and Dentistry 17 30%
Biochemistry, Genetics and Molecular Biology 4 7%
Nursing and Health Professions 4 7%
Materials Science 2 4%
Neuroscience 2 4%
Other 7 13%
Unknown 20 36%