Descrição dos primeiros casos de febre pelo vírus Zika investigados em municípios da região Nordeste do Brasil, 2015

Francieli Fontana Sutile Tardetti Fantinato, Emerson Luiz Lima Araújo, Igor Gonçalves Ribeiro, Marcia Regina de Andrade, Anna Livia de Medeiros Dantas, Jakeline Maria Trinta Rios, Odila Márcia Vinhas da Silva, Maria do Socorro da Silva, Renata Valeria Nóbrega, Daniel de Araújo Batista, Priscila Leal e Leite, Eduardo Saad, Jadher Percio, Elionardo Andrade Resende, Priscila Bochi de Souza, Marcelo Yoshito Wada, Francieli Fontana Sutile Tardetti Fantinato, Emerson Luiz Lima Araújo, Igor Gonçalves Ribeiro, Marcia Regina de Andrade, Anna Livia de Medeiros Dantas, Jakeline Maria Trinta Rios, Odila Márcia Vinhas da Silva, Maria do Socorro da Silva, Renata Valeria Nóbrega, Daniel de Araújo Batista, Priscila Leal e Leite, Eduardo Saad, Jadher Percio, Elionardo Andrade Resende, Priscila Bochi de Souza, Marcelo Yoshito Wada

to confirm Zika virus circulation and discard other etiological agents in an outbreak occurred in the states of Rio Grande do Norte, Maranhão and Paraíba, in May, 2015. this is a case series descriptive study with residents in Natal-RN, Barra do Corda-MA, São Luis-MA and João Pessoa-PB, with 20 cases in each state, presenting rash, absent or mild fever and one of the following signs/symptoms: conjunctival hyperemia, arthralgia or limb edema; RT-PCR/isolation tests for Zika, enterovirus and respiratory viruses, and serology tests (dengue, rubella and parvovirus B19) were performed. the main symptoms were rash (n=60), pruritus (n=54), and arthralgia (n=47); 51 individuals did not present fever; Zika virus was identified in 18 cases (12 in Paraíba, four in Maranhão and two in Rio Grande do Norte), and antibodies to dengue, in 14 cases. the symptoms were consistent with Zika virus fever; there was laboratory confirmation for Zika and dengue.