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Microbiological and epidemiological study of infectious keratitis in children and adolescents

Overview of attention for article published in Arquivos Brasileiros de Oftalmologia, January 2016
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Title
Microbiological and epidemiological study of infectious keratitis in children and adolescents
Published in
Arquivos Brasileiros de Oftalmologia, January 2016
DOI 10.5935/0004-2749.20160084
Pubmed ID
Authors

Maria Cecilia Zorat Yu, Ana Luisa Höfling-Lima, Guilherme Henrique Campos Furtado

Abstract

To analyze epidemiological and microbiological aspects of microbial keratitis in children and adolescents. This retrospective cohort study was conducted at the Department of Ophthalmology and Visual Science, Escola Paulista de Medicina, Universidade Federal de São Paulo, between July 15, 1975, and December 31, 2010. We analyzed corneal samples from 859 patients with clinical suspicion of infectious keratitis, comparing epidemiological and microbiological characteristics of bacterial keratitis with those of non-bacterial and non-viral keratitis. We also compared Gram-positive and Gram-negative pathogens in patients with bacterial keratitis. We created a susceptibility profile of the bacterial microorganisms studied. Of the 859 patients, 346 (40.3%) showed positive culture results for non-viral microorganisms. Teenagers (13-18 years) made up the group with the highest number of patients with keratitis (164, 47.4%). The most frequent risk factors for keratitis were trauma (33.5%) and previous ocular surgery (24.9%). Gram-positive bacteria (71.8%) were the most often isolated, with coagulase-negative Staphylococcus (23.8%) the most prevalent microorganism. Logistic regression analysis showed age (p=0.002), topical antimicrobial drug use (p=0.01), and trauma due to non-chemical burns (p=0.005) were risk factors for non-bacterial keratitis. Age (p=0.01) was also a risk factor for Gram-negative bacterial keratitis. Our study showed that in the age range studied, the prevalence of keratitis caused by Gram-negative bacteria or by the non-viral microorganisms evaluated increases with age. Previous use of topical antimicrobial drug and trauma due to non-chemical burns are associated with non-bacterial keratitis. Knowledge of the risk factors and the microorganisms involved may help improve treatment of keratitis in children and adolescents and minimize visual impairment.

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Mendeley readers

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The data shown below were compiled from readership statistics for 51 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
Unknown 51 100%

Demographic breakdown

Readers by professional status Count As %
Researcher 9 18%
Student > Bachelor 5 10%
Student > Master 5 10%
Student > Ph. D. Student 4 8%
Student > Postgraduate 4 8%
Other 7 14%
Unknown 17 33%
Readers by discipline Count As %
Medicine and Dentistry 13 25%
Agricultural and Biological Sciences 4 8%
Immunology and Microbiology 3 6%
Biochemistry, Genetics and Molecular Biology 2 4%
Environmental Science 1 2%
Other 7 14%
Unknown 21 41%
Attention Score in Context

Attention Score in Context

This research output has an Altmetric Attention Score of 1. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 27 July 2017.
All research outputs
#20,655,488
of 25,373,627 outputs
Outputs from Arquivos Brasileiros de Oftalmologia
#255
of 446 outputs
Outputs of similar age
#295,035
of 399,662 outputs
Outputs of similar age from Arquivos Brasileiros de Oftalmologia
#23
of 43 outputs
Altmetric has tracked 25,373,627 research outputs across all sources so far. This one is in the 10th percentile – i.e., 10% of other outputs scored the same or lower than it.
So far Altmetric has tracked 446 research outputs from this source. They receive a mean Attention Score of 2.5. This one is in the 28th percentile – i.e., 28% of its peers scored the same or lower than it.
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