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X Demographics
Mendeley readers
Attention Score in Context
| Title |
Nefrotoxicidade aguda da cisplatina: mecanismos moleculares
|
|---|---|
| Published in |
Jornal Brasileiro de Nefrologia, December 2013
|
| DOI | 10.5935/0101-2800.20130052 |
| Pubmed ID | |
| Authors |
Luis Alberto Batista Peres, Ademar Dantas da Cunha Júnior |
| Abstract |
The nephrotoxic drugs have been responsible for about 20% of AKI episodes in inpatients and outpatients. The cisplatin nephrotoxicity is a major limiting factors in 20% of patients who have received the drug, triggering injuries in renal tubular epithelial cells. Cisplatin toxicity is determined by the target tissue and cells accumulation besides the interaction with various subcellular structures and macromolecules. Cisplatin accumulates and interferes with the functioning of different organelles such as mitochondria, lysosomes, endoplasmic reticulum, nuclei and cell membranes, causing inflammation and cell death. This review aims to define the pathophysiology and biochemistry of the cisplatin nephrotoxicity, reviewing the main molecular mechanisms that lead to tubular cisplatin toxicity. |
X Demographics
The data shown below were collected from the profiles of 4 X users who shared this research output. Click here to find out more about how the information was compiled.
Geographical breakdown
| Country | Count | As % |
|---|---|---|
| Spain | 1 | 25% |
| Unknown | 3 | 75% |
Demographic breakdown
| Type | Count | As % |
|---|---|---|
| Members of the public | 4 | 100% |
Mendeley readers
The data shown below were compiled from readership statistics for 194 Mendeley readers of this research output. Click here to see the associated Mendeley record.
Geographical breakdown
| Country | Count | As % |
|---|---|---|
| Unknown | 194 | 100% |
Demographic breakdown
| Readers by professional status | Count | As % |
|---|---|---|
| Student > Master | 31 | 16% |
| Student > Bachelor | 30 | 15% |
| Researcher | 19 | 10% |
| Student > Ph. D. Student | 17 | 9% |
| Other | 8 | 4% |
| Other | 24 | 12% |
| Unknown | 65 | 34% |
| Readers by discipline | Count | As % |
|---|---|---|
| Pharmacology, Toxicology and Pharmaceutical Science | 36 | 19% |
| Biochemistry, Genetics and Molecular Biology | 22 | 11% |
| Medicine and Dentistry | 22 | 11% |
| Agricultural and Biological Sciences | 17 | 9% |
| Chemistry | 11 | 6% |
| Other | 14 | 7% |
| Unknown | 72 | 37% |
Attention Score in Context
This research output has an Altmetric Attention Score of 2. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 17 January 2014.
All research outputs
#15,740,505
of 25,374,917 outputs
Outputs from Jornal Brasileiro de Nefrologia
#138
of 364 outputs
Outputs of similar age
#185,239
of 320,499 outputs
Outputs of similar age from Jornal Brasileiro de Nefrologia
#9
of 23 outputs
Altmetric has tracked 25,374,917 research outputs across all sources so far. This one is in the 37th percentile – i.e., 37% of other outputs scored the same or lower than it.
So far Altmetric has tracked 364 research outputs from this source. They receive a mean Attention Score of 2.5. This one has gotten more attention than average, scoring higher than 61% of its peers.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 320,499 tracked outputs that were published within six weeks on either side of this one in any source. This one is in the 41st percentile – i.e., 41% of its contemporaries scored the same or lower than it.
We're also able to compare this research output to 23 others from the same source and published within six weeks on either side of this one. This one has gotten more attention than average, scoring higher than 56% of its contemporaries.