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Factors associated with moderate or severe left atrioventricular valve regurgitation within 30 days of repair of incomplete atrioventricular septal defect

Overview of attention for article published in Revista Brasileira de Cirurgia Cardiovascular, January 2015
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Title
Factors associated with moderate or severe left atrioventricular valve regurgitation within 30 days of repair of incomplete atrioventricular septal defect
Published in
Revista Brasileira de Cirurgia Cardiovascular, January 2015
DOI 10.5935/1678-9741.20150026
Pubmed ID
Authors

Marcelo Felipe Kozak, Ana Carolina Leiroz Ferreira Botelho Maisano Kozak, Carlos Henrique De Marchi, Moacyr Fernandes de Godoy, Ulisses Alexandre Croti, Airton Camacho Moscardini

Abstract

Left atrioventricular valve regurgitation is the most concerning residual lesion after surgical correction of atrioventricular septal defect. To determine factors associated with moderate or greater left atrioventricular valve regurgitation within 30 days of surgical repair of incomplete atrioventricular septal defect. We assessed the results of 51 consecutive patients 14 years-old and younger presenting with incomplete atrioventricular septal defect that were operated on at our practice between 2002 and 2010. The following variables were considered: age, weight, absence of Down syndrome, grade of preoperative left atrioventricular valve regurgitation, abnormalities on the left atrioventricular valve and the use of annuloplasty. The median age was 4.1 years; the median weight was 13.4 Kg; 37.2% had Down syndrome. At the time of preoperative evaluation, there were 23 cases with moderate or greater left atrioventricular valve regurgitation (45.1%). Abnormalities on the left atrioventricular valve were found in 17.6%; annuloplasty was performed in 21.6%. At the time of postoperative evaluation, there were 12 cases with moderate or greater left atrioventricular valve regurgitation (23.5%). The variation between pre- and postoperative grades of left atrioventricular valve regurgitation of patients with atrioventricular valve malformation did not reach significance (P=0.26), unlike patients without such abnormalities (P=0.016). During univariate analysis, only absence of Down syndrome was statistically significant (P=0.02). However, after a multivariate analysis, none of the factors reached significance. None of the factors studied was determinant of a moderate or greater left atrioventricular valve regurgitation within the first 30 days of repair of incomplete atrioventricular septal defect in the sample. Patients without abnormalities on the left atrioventricular valve benefit more of the operation.

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Mendeley readers

The data shown below were compiled from readership statistics for 11 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
Unknown 11 100%

Demographic breakdown

Readers by professional status Count As %
Student > Ph. D. Student 1 9%
Student > Postgraduate 1 9%
Student > Master 1 9%
Unknown 8 73%
Readers by discipline Count As %
Biochemistry, Genetics and Molecular Biology 1 9%
Nursing and Health Professions 1 9%
Medicine and Dentistry 1 9%
Unknown 8 73%