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Evaluation of microvessel density and p53 expression in pancreatic adenocarcinoma

Overview of attention for article published in Clinics, June 2016
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Title
Evaluation of microvessel density and p53 expression in pancreatic adenocarcinoma
Published in
Clinics, June 2016
DOI 10.6061/clinics/2016(06)05
Pubmed ID
Authors

Ricardo Jureidini, José Eduardo Monteiro da Cunha, Flavio Takeda, Guilherme Naccache Namur, Thiago Costa Ribeiro, Rosely Patzina, Estela RR Figueira, Ulysses Ribeiro, Telesforo Bacchella, Ivan Cecconello

Abstract

To evaluate the prognostic significance of microvessel density and p53 expression in pancreatic cancer. Between 2008 and 2012, 49 patients with pancreatic adenocarcinoma underwent resection with curative intention. The resected specimens were immunohistochemically stained with anti-p53 and anti-CD34 antibodies. Microvessel density was assessed by counting vessels within ten areas of each tumoral section a highpower microscope. The microvessel density ranged from 21.2 to 54.2 vessels/mm2. Positive nuclear staining for p53 was found in 20 patients (40.6%). The overall median survival rate after resection was 24.1 months and there were no differences in survival rates related to microvessel density or p53 positivity. Microvessel density was associated with tumor diameter greater than 3.0 cm and with R0 resection failure. Microvessel density was associated with R1 resection and with larger tumors. p53 expression was not correlated with intratumoral microvessel density in pancreatic adenocarcinoma.

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Mendeley readers

Mendeley readers

The data shown below were compiled from readership statistics for 16 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
Unknown 16 100%

Demographic breakdown

Readers by professional status Count As %
Student > Doctoral Student 3 19%
Student > Master 3 19%
Student > Bachelor 2 13%
Professor > Associate Professor 2 13%
Student > Ph. D. Student 1 6%
Other 2 13%
Unknown 3 19%
Readers by discipline Count As %
Medicine and Dentistry 9 56%
Materials Science 1 6%
Arts and Humanities 1 6%
Unknown 5 31%
Attention Score in Context

Attention Score in Context

This research output has an Altmetric Attention Score of 1. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 21 July 2016.
All research outputs
#20,653,708
of 25,371,288 outputs
Outputs from Clinics
#861
of 1,215 outputs
Outputs of similar age
#269,925
of 353,651 outputs
Outputs of similar age from Clinics
#7
of 10 outputs
Altmetric has tracked 25,371,288 research outputs across all sources so far. This one is in the 10th percentile – i.e., 10% of other outputs scored the same or lower than it.
So far Altmetric has tracked 1,215 research outputs from this source. They typically receive a little more attention than average, with a mean Attention Score of 7.2. This one is in the 17th percentile – i.e., 17% of its peers scored the same or lower than it.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 353,651 tracked outputs that were published within six weeks on either side of this one in any source. This one is in the 12th percentile – i.e., 12% of its contemporaries scored the same or lower than it.
We're also able to compare this research output to 10 others from the same source and published within six weeks on either side of this one. This one has scored higher than 3 of them.