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Adverse reactions associated with meningococcal group B vaccine (4CMenB) in adults in special situations

Overview of attention for article published in Farmacia Hospitalaria, September 2018
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  • Good Attention Score compared to outputs of the same age (66th percentile)
  • Above-average Attention Score compared to outputs of the same age and source (60th percentile)

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14 Mendeley
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Title
Adverse reactions associated with meningococcal group B vaccine (4CMenB) in adults in special situations
Published in
Farmacia Hospitalaria, September 2018
DOI 10.7399/fh.10989
Pubmed ID
Authors

María Fernández-Prada, Carmen Martínez-Ortega, Lara Hidalgo-Peña, Clara Álvarez-Vázquez, Rodrigo Aguirre-Del Pino, Ismael Huerta-González

Abstract

To know the safety profile of the 4CMenB vaccine in adults in special situations. Security prospective study of phase IV. Inclusion criteria and some  vaccination conditions were applied. The adverse reactions described in the data  sheet were collected. The adverse reactions evaluation was performed 24 hours  after vaccination ("requested") and during the first seven days ("not  requested"). 72 patients were included (54.2% men, mean age 52.5 years, 81.9%  anatomic asplenia). The frequency of fever > 38 ºC in the first 24 hours of  vaccination was higher than the observed in the summary of product characteristics for the group of adults (12.5% vs. not known). More than 75% of the patients reported local pain in the first hours [average of the Analog Visual Scale score 3.22 (95% CI: 2.67-3.76) in the first dose and 3.23 (95% CI: 2.69-3.78) in the second dose]. There were no statistically significant differences. 97.22% registered symptoms until 7 days  after vaccination. 4CMenB® shows a good safety profile in adults in special situations. The frequency of fever > 38 ºC is higher than expected. Local  pain is the most frequently recorded adverse reactions, but the intensity is low.  These results suggest a review of the situation in order to suggest a possible  modification of the summary of product characteristics of the vaccine.

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X Demographics

The data shown below were collected from the profiles of 5 X users who shared this research output. Click here to find out more about how the information was compiled.
Mendeley readers

Mendeley readers

The data shown below were compiled from readership statistics for 14 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
Unknown 14 100%

Demographic breakdown

Readers by professional status Count As %
Student > Bachelor 3 21%
Researcher 2 14%
Student > Ph. D. Student 1 7%
Other 1 7%
Student > Master 1 7%
Other 1 7%
Unknown 5 36%
Readers by discipline Count As %
Medicine and Dentistry 3 21%
Nursing and Health Professions 2 14%
Arts and Humanities 1 7%
Pharmacology, Toxicology and Pharmaceutical Science 1 7%
Immunology and Microbiology 1 7%
Other 1 7%
Unknown 5 36%
Attention Score in Context

Attention Score in Context

This research output has an Altmetric Attention Score of 5. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 24 October 2021.
All research outputs
#7,028,608
of 25,385,509 outputs
Outputs from Farmacia Hospitalaria
#63
of 368 outputs
Outputs of similar age
#114,844
of 345,739 outputs
Outputs of similar age from Farmacia Hospitalaria
#2
of 5 outputs
Altmetric has tracked 25,385,509 research outputs across all sources so far. This one has received more attention than most of these and is in the 72nd percentile.
So far Altmetric has tracked 368 research outputs from this source. They receive a mean Attention Score of 2.7. This one has done well, scoring higher than 82% of its peers.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 345,739 tracked outputs that were published within six weeks on either side of this one in any source. This one has gotten more attention than average, scoring higher than 66% of its contemporaries.
We're also able to compare this research output to 5 others from the same source and published within six weeks on either side of this one. This one has scored higher than 3 of them.