The Bioreductive Prodrug PR-104A Is Activated under Aerobic Conditions by Human Aldo-Keto Reductase 1C3

Overview of attention for article published in Cancer Research, February 2010

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In the top 25% of all research outputs scored by Altmetric
High Attention Score compared to outputs of the same age (91st percentile)
High Attention Score compared to outputs of the same age and source (80th percentile)

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patent: 11 patents

wikipedia: 1 Wikipedia page

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So far, Altmetric has seen 11 patents that reference this research output.

CORRELATION OF AKR1C3 ENZYME EXPRESSION LEVEL WITH KRAS MUTATION, AND MEDICAL USE

Application WO-2024251193-A1

World Intellectual Property Organisation (WIPO)

12 Dec 2024

TRICYCLIC AKR1C3 DEPENDENT KARS INHIBITORS

Application EP-4349839-A2

European Patent Office

10 Apr 2024

COMBINATION THERAPY BY USING AKR1C3-ACTIVATED COMPOUND WITH IMMUNE CHECKPOINT INHIBITOR

Application EP-4329745-A1

European Patent Office

06 Mar 2024

METHODS OF TRICYCLIC AKR1C3 DEPENDENT KARS INHIBITOR DOSING FIELD OF THE INVENTION

Application WO-2024023641-A1

World Intellectual Property Organisation (WIPO)

01 Feb 2024

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