Von Willebrand factor is unique among coagulation factors by virtue of its highly multimeric structure, which allows it to function as an endogenous sensor of hemodynamic forces.(1) Under conditions of low shear stress (below the usual physiologic range), von Willebrand factor self-associates into compacted, high-molecular-weight (HMW) multimers that are unable to promote platelet adhesion. During physiologic shear stress (shear rate of 100 to 5000 sec-1), von Willebrand factor undergoes partial unfolding and elongation, exposing binding sites for platelets and collagen and allowing the metalloprotease ADAMTS13 to regulate the size distribution of the HMW multimers by cleaving von Willebrand factor . . .
This research output has an Altmetric Attention Score of 36. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 02 May 2017.
All research outputs
#1,403,538
of 33,220,432 outputs
Outputs from New England Journal of Medicine
#12,339
of 37,831 outputs
Outputs of similar age
#18,173
of 328,601 outputs
Outputs of similar age from New England Journal of Medicine
#175
of 310 outputs
Altmetric has tracked 33,220,432 research outputs across all sources so far. Compared to these this one has done particularly well and is in the 95th percentile: it's in the top 5% of all research outputs ever tracked by Altmetric.
So far Altmetric has tracked 37,831 research outputs from this source. They typically receive a lot more attention than average, with a mean Attention Score of 119.9. This one has gotten more attention than average, scoring higher than 67% of its peers.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 328,601 tracked outputs that were published within six weeks on either side of this one in any source. This one has done particularly well, scoring higher than 94% of its contemporaries.
We're also able to compare this research output to 310 others from the same source and published within six weeks on either side of this one. This one is in the 43rd percentile – i.e., 43% of its contemporaries scored the same or lower than it.
