Complement Factor H Variant Increases the Risk of Age-Related Macular Degeneration

We also ran a (desperately underpowered) GWAS in our cohort. Naturally, no novel associations were found at genome-wide significance. The chr1 peak is at CFH, which was discovered already in 2005 in very small samples. https://t.co/vqezfb3UQ5 https://t…

13.) Among all research on the FH protein family, age-related macular degeneration (#AMD) is the most studied. In 2005, 3⃣ studies showed that a🧬variant in FH contributed to the susceptibility of AMD: - https://t.co/fDGKCwGnVo - https://t.co/ktGS6lVv1U …