Sequence variants at CYP1A1–CYP1A2 and AHR associate with coffee consumption

Overview of attention for article published in Human Molecular Genetics, February 2011

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@redcoast A particular enzyme in the liver processes caffeine, the #CYP1A2 enzyme, which unsurprisingly is encoded by the CYP1A2 gene. Genetic variants exist for this gene, meaning some people can LIVE off coffee (me! 🙋‍♂️); others get unpleasant side-ef…

@Dirtdragonmom no worries, a friend of mine is ultra-sensitive to caffeine, can't drink it at all. There's a particular enzyme in the liver; mutations/variants in that determine one's sensitivity. My theory is I have the strongest caffeine-eating enzyme…

@lcpilling Reminds me of coffee intake hits we published in 2011 https://t.co/g4p2dRXrT0

@doctorveera @Ceballos_Gene I had fun working on the subject a decade ago etecting cyp1a1 and ahr assoc https://t.co/RUr9J3pbqk

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