Interaction between the Corticotropin-Releasing Factor System and Hypocretins (Orexins): A Novel Circuit Mediating Stress Response

Overview of attention for article published in Journal of Neuroscience, December 2004

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In the top 25% of all research outputs scored by Altmetric
High Attention Score compared to outputs of the same age (86th percentile)
Good Attention Score compared to outputs of the same age and source (76th percentile)

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patent: 21 patents
f1000: 1 research highlight platform

podcasts: 1 podcast

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So far, Altmetric has seen 21 patents that reference this research output.

Disubstituted octahydropyrrolo[3,4-c]pyrroles as orexin receptor modulators

Grant US-12378254-B2

United States of America

05 Aug 2025

Methods of treating depression using orexin-2 receptor antagonists

Grant US-12201634-B2

United States of America

21 Jan 2025

Disubstituted octahydropyrrolo[3,4-c]pyrroles as orexin receptor modulators

Grant US-11667644-B2

United States of America

06 Jun 2023

Methods of treating depression using orexin-2 receptor antagonists

Grant US-11241432-B2

United States of America

08 Feb 2022

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