Four distinct trajectories of tau deposition identified in Alzheimer’s disease

[🧵4] this is particularly important, since patterns of tau as captured by PET scans vary markedly across individuals and the role of inter-individual variability in shaping these patterns remains underexplored. e.g. see: rdcu.be/eJKD5

🧵8/ We also explored why different Alzheimer's patients show unique tau patterns (subtypes)? We tested patterns from the four Alzheimer’s subtypes @jwvogel.bsky.social (www.nature.com/articles/s41...), and identified two (of the four subtypes) with espec…