Enrichment of NPC1-deficient cells with the lipid LBPA stimulates autophagy, improves lysosomal function, and reduces cholesterol storage

RT @elsbiomedchem: lnytska et al. provide a mechanistic basis supporting cellular LBPA as a potential new target for therapeutic interventi…

Ilnytska et al. provide a mechanistic basis supporting cellular LBPA as a potential new target for therapeutic intervention in Niemann-Pick C disease @RutgersResearch @RutgersU #cholesterol #autophagy https://t.co/NelFAXOEVE https://t.co/bUZHRqypfY

Ilnytska et al. show that phosphatidylglycerol incubation/lipid lysobisphosphatidic acid enrichment significantly improves the compromised autophagic flux associated with NPC1 disease. https://t.co/NelFAXOEVE @RutgersResearch @RutgersU

We are proud to have helped with this work from the Storch Lab! Enrichment of NPC1-deficient cells with the lipid LBPA stimulates autophagy, improves lysosomal function, and reduc… https://t.co/4IZo6OL6pz