Modulation of CGRP-Induced Light Aversion in Wild-Type Mice by a 5-HT1B/D Agonist

Overview of attention for article published in Journal of Neuroscience, October 2012

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Dr. Recober: in nestin/hRAMP1 mice, CGRP induces photophobia & CGRP antagonist blocks photophobia #AHS12AZ read more @ http://t.co/o2i19QrB

片頭痛時には光に過敏になるが、マウスへのCGRP脳内投与は光嫌悪を誘発する。この外来性CGRP誘発光嫌悪は片頭痛薬リザトリプタン（5HT1B/D作動薬）で抑制された。トリプタンの光過敏抑制は内在性CGRP抑制以外の機序によると考えられた。http://t.co/y8HYnWPQ

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