Disrupting progression of the yeast Hsp90 folding pathway at different transition points results in client-specific maturation defects

RT @GeneticsGSA: By analyzing mutants of Hsp90, a chaperone that impacts the function of 10-15% of the proteome, Hohrman et al. show that d…

By analyzing mutants of Hsp90, a chaperone that impacts the function of 10-15% of the proteome, Hohrman et al. show that disrupting the progression of the folding pathway at different stages results in client-specific maturation defects. #GENETICS https…